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R G Shulman

Explore the profile of R G Shulman including associated specialties, affiliations and a list of published articles. Areas
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Articles 295
Citations 6300
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Recent Articles
11.
Hyder F, Shulman R, Rothman D
Adv Exp Med Biol . 2000 Feb; 471:99-110. PMID: 10659136
No abstract available.
12.
Rothman D, Sibson N, Hyder F, Shen J, Behar K, Shulman R
Philos Trans R Soc Lond B Biol Sci . 1999 Aug; 354(1387):1165-77. PMID: 10466144
In this article we review recent studies, primarily from our laboratory, using 13C NMR (nuclear magnetic resonance) to non-invasively measure the rate of the glutamate-glutamine neurotransmitter cycle in the cortex...
13.
Shen J, Petersen K, Behar K, Brown P, Nixon T, MASON G, et al.
Proc Natl Acad Sci U S A . 1999 Jul; 96(14):8235-40. PMID: 10393978
Recent 13C NMR studies in rat models have shown that the glutamate/glutamine cycle is highly active in the cerebral cortex and is coupled to incremental glucose oxidation in an approximately...
14.
Shulman R, Rothman D, Hyder F
Proc Natl Acad Sci U S A . 1999 Mar; 96(6):3245-50. PMID: 10077669
Focal changes in the cerebral metabolic rate of glucose utilization (CMRglc) are small (10-40%) during sensory activation in awake humans, as well as in awake rodents and primates (20-50%). They...
15.
Magistretti P, Pellerin L, Rothman D, Shulman R
Science . 1999 Feb; 283(5401):496-7. PMID: 9988650
No abstract available.
16.
Shen J, Sibson N, Cline G, Behar K, Rothman D, Shulman R
Dev Neurosci . 1998 Oct; 20(4-5):434-43. PMID: 9778582
Ammonia transport and glutamine synthesis were studied in the hyperammonaemic rat brain in vivo using 15N-NMR spectroscopy at a plasma ammonia level of approximately 0.39 mM raised via an intravenous...
17.
Sibson N, Shen J, MASON G, Rothman D, Behar K, Shulman R
Dev Neurosci . 1998 Oct; 20(4-5):321-30. PMID: 9778568
The use of in vivo 13C nuclear magnetic resonance spectroscopy (NMR) has established the pathways of functional interaction between neurons and astrocytes in the mammalian brain and enabled quantitation of...
18.
Shulman R, Rothman D
Proc Natl Acad Sci U S A . 1998 Sep; 95(20):11993-8. PMID: 9751778
Functional imaging experiments, in particular positron-emission tomography and functional magnetic resonance imaging, can be analyzed either in psychological terms or on the basis of neuroscience. In the usual psychological interpretation,...
19.
Hyder F, Shulman R, Rothman D
J Appl Physiol (1985) . 1998 Aug; 85(2):554-64. PMID: 9688733
On the basis of the assumption that oxygen delivery across the endothelium is proportional to capillary plasma PO2, a model is presented that links cerebral metabolic rate of oxygen utilization...
20.
Yang X, Renken R, Hyder F, Siddeek M, Greer C, Shepherd G, et al.
Proc Natl Acad Sci U S A . 1998 Jun; 95(13):7715-20. PMID: 9636216
We have applied functional MRI (fMRI) based on blood oxygenation level-dependent (BOLD) image-contrast to map odor-elicited olfactory responses at the laminar level in the rat olfactory bulb (OB) elicited by...