R E Kellems
Overview
Explore the profile of R E Kellems including associated specialties, affiliations and a list of published articles.
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Articles
83
Citations
1693
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0
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Recent Articles
1.
Wang W, Irani R, Zhang Y, Kellems R, Xia Y
Pregnancy Hypertens
. 2015 Jun;
2(3):214.
PMID: 26105284
Introduction: Preeclampsia (PE) is associated with alterations in the renin-angiotensin system due to the presence of autoantibodies that activate the major angiotensin receptor, AT1R. The resulting chronic activation of the...
2.
Liu C, Wang W, Parchim N, Irani R, Ning C, Sun K, et al.
Pregnancy Hypertens
. 2015 Jun;
2(3):208.
PMID: 26105271
Introduction: Preeclampsia (PE) is highly associated with the presence of autoantibodies that activate the major angiotensin receptor, AT1R. These autoantibodies (termed AT1-AA) cause most features of PE when introduced into...
3.
Schaubach B, Wen H, Kellems R
Placenta
. 2005 Dec;
27(2-3):269-77.
PMID: 16338472
The formation of the trophoblast cell lineage of the placenta is one of the first developmental events to occur in mammalian embryogenesis. To understand the mechanisms of gene regulation in...
4.
Wen H, Abbasi S, Kellems R, Xia Y
Placenta
. 2005 Apr;
26 Suppl A:S63-9.
PMID: 15837070
The proliferation and differentiation of trophoblast cells is under the control of a variety of hormones and growth factors and is influenced by nutrient availability. The intracellular signaling pathways acting...
5.
Wen H, Xia Y, Young M, Taegtmeyer H, Kellems R
J Cell Mol Med
. 2002 Aug;
6(2):235-43.
PMID: 12169208
Adenylosuccinate synthetase 1 (ADSS1) functions as an important component in adenine nucleotide biosynthesis and is abundant in the heart. Here we report that the Adss1 gene is up-regulated in two...
6.
Van De Wiel C, Hooker S, Laurent A, VAUGHN J, Blackburn M, Kellems R, et al.
Adv Exp Med Biol
. 2002 Jan;
486:65-70.
PMID: 11783529
No abstract available.
7.
Aldrich M, Blackburn M, Datta S, Kellems R
Adv Exp Med Biol
. 2002 Jan;
486:57-63.
PMID: 11783528
No abstract available.
8.
Apasov S, Blackburn M, Kellems R, Smith P, Sitkovsky M
J Clin Invest
. 2001 Jul;
108(1):131-41.
PMID: 11435465
Adenosine deaminase (ADA) deficiency in humans results in a severe combined immunodeficiency (SCID). This immunodeficiency is associated with severe disturbances in purine metabolism that are thought to mediate lymphotoxicity. The...
9.
Thompson L, Van de Wiele C, Laurent A, Hooker S, VAUGHN J, Jiang H, et al.
J Clin Invest
. 2000 Nov;
106(9):1149-57.
PMID: 11067867
Murine fetal thymic organ culture was used to investigate the mechanism by which adenosine deaminase (ADA) deficiency causes T-cell immunodeficiency. C57BL/6 fetal thymuses treated with the specific ADA inhibitor 2'-deoxycoformycin...
10.
Blackburn M, Aldrich M, Volmer J, Chen W, Zhong H, Kelly S, et al.
J Biol Chem
. 2000 Jul;
275(41):32114-21.
PMID: 10908569
Adenosine deaminase (ADA) deficiency results in a combined immunodeficiency brought about by the immunotoxic properties of elevated ADA substrates. Additional non-lymphoid abnormalities are associated with ADA deficiency, however, little is...