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R C Boucher

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Articles 256
Citations 8622
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Recent Articles
1.
Ward J, Cornaby C, Kato T, Gilmore R, Bunch D, Miller M, et al.
Placenta . 2022 May; 123:12-23. PMID: 35512490
Introduction: The effect of SARS-CoV-2 severity or the trimester of infection in pregnant mothers, placentas, and infants is not fully understood. Methods: A retrospective, observational cohort study in Chapel Hill,...
2.
Livraghi-Butrico A, Grubb B, Wilkinson K, Volmer A, Burns K, Evans C, et al.
Mucosal Immunol . 2017 Apr; 10(3):829. PMID: 28435155
No abstract available.
3.
Ghosh A, Boucher R, Tarran R
Cell Mol Life Sci . 2015 Jun; 72(19):3637-52. PMID: 26068443
Chronic obstructive pulmonary disease (COPD) is one of the prevalent causes of worldwide mortality and encompasses two major clinical phenotypes, i.e., chronic bronchitis (CB) and emphysema. The most common cause...
4.
Bennett W, Wu J, Fuller F, Balcazar J, Zeman K, Duckworth H, et al.
J Appl Physiol (1985) . 2015 Apr; 118(12):1483-90. PMID: 25911685
Inhalation of hypertonic saline (HS) acutely enhances mucociliary clearance (MC) in both health and disease. In patients with cystic fibrosis (CF), repeated use of HS causes a sustained improvement in...
5.
Livraghi-Butrico A, Kelly E, Klem E, Dang H, Wolfgang M, Boucher R, et al.
Mucosal Immunol . 2012 Mar; 5(4):397-408. PMID: 22419116
It has been postulated that mucus stasis is central to the pathogenesis of obstructive lung diseases. In Scnn1b-transgenic (Scnn1b-Tg⁺ mice, airway-targeted overexpression of the epithelial Na⁺ channel β subunit causes...
6.
Grubb B, ONeal W, Ostrowski L, Kreda S, Button B, Boucher R
Am J Physiol Lung Cell Mol Physiol . 2011 Oct; 302(2):L238-47. PMID: 22003093
The relationships between airway epithelial Cl(-) secretion-Na(+) absorption balance, airway surface liquid (ASL) homeostasis, and lung disease were investigated in selected transgenic mice. 1) To determine if transgenic overexpression of...
7.
Tunney M, Klem E, Fodor A, Gilpin D, Moriarty T, McGrath S, et al.
Thorax . 2011 Jan; 66(7):579-84. PMID: 21270069
Background: Anaerobic bacteria are increasingly regarded as important in cystic fibrosis (CF) pulmonary infection. The aim of this study was to determine the effect of antibiotic treatment on aerobic and...
8.
Carson J, Collier A, Knowles M, Boucher R
Am J Anat . 2010 Aug; 173(4):257-68. PMID: 20726125
Cell membranes of normal human nasal and tracheal epithelium were characterized by means of freeze-fracture preparations. These investigations illustrated a predictable variability in the distribution of membrane-associated particles on PF-faces...
9.
Grubb B, Rogers T, Boucher R, Ostrowski L
Am J Physiol Cell Physiol . 2009 Mar; 296(6):C1301-9. PMID: 19321738
The nasal epithelium of the cystic fibrosis (CF) mouse has been used extensively in CF research because it exhibits ion transport defects similar to those of human CF airways. This...
10.
Thelin W, Brennan M, Lockhart P, Singh M, Fox P, Papas A, et al.
Oral Dis . 2009 Feb; 14(8):683-9. PMID: 19193197
Autoimmune disorders, medical interventions, and aging are all known to be associated with salivary gland hypofunction, which results in the uncomfortable feeling of dry mouth (xerostomia) and significantly diminished oral...