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R A Gadski

Explore the profile of R A Gadski including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 167
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Recent Articles
1.
Corominola H, Conner L, Beavers L, Gadski R, Johnson D, Caro J
Diabetes . 2001 Nov; 50(12):2822-30. PMID: 11723066
Obesity is associated with an increased risk for developing type 2 diabetes, insulin resistance, hypertension, dyslipidemia, cardiovascular disease, respiratory dysfunction, and certain forms of cancer. Insulin resistance in many type...
2.
Statnick M, Beavers L, Conner L, Corominola H, Johnson D, Hammond C, et al.
Int J Exp Diabetes Res . 2001 Jul; 1(2):81-8. PMID: 11469400
We have screened a subtracted cDNA library in order to identify differentially expressed genes in omental adipose tissue of human patients with Type 2 diabetes. One clone (#1738) showed a...
3.
Gehlert D, Yang P, George C, Wang Y, Schober D, Gackenheimer S, et al.
Peptides . 2001 Apr; 22(3):343-50. PMID: 11287088
Neuropeptide Y (NPY) is a 36 amino acid peptide that is abundant in the brain and peripheral nervous system. NPY has a variety of effects when administered into the brain...
4.
Lin H, Rampersaud A, Beavers L, McClure D, Gardner A, Eacho P, et al.
Steroids . 1999 Sep; 64(10):735-41. PMID: 10498032
4alpha-(2-Propenyl)-5alpha-cholest-24-en-3alpha-ol (3) was shown recently in a Chinese hamster ovary (CHO) cell-based low-density lipoprotein receptor/luciferase (LDLR/Luc) assay to be a potent transcriptional activator of the LDL receptor promoter in the...
5.
Lin H, Rampersaud A, Richett M, Harper R, Beavers L, McClure D, et al.
Steroids . 1999 Jul; 64(3):217-27. PMID: 10400383
4Alpha-(2-propenyl)-5alpha-cholestan-3alpha-ol (LY295427) was previously identified from a Chinese hamster ovary (CHO) cell-based low density lipoprotein receptor/luciferase (LDLR/Luc) assay to be a potent transcriptional activator of the LDL receptor promoter in...
6.
Bensch W, Gadski R, Bean J, Beavers L, Schmidt R, Perry D, et al.
J Pharmacol Exp Ther . 1999 Mar; 289(1):85-92. PMID: 10086991
The action of LY295427 [(3alpha,4alpha, 5alpha)-4-(2-propenylcholestan-3-ol)], a compound that derepresses low-density lipoprotein receptor (LDL-R) expression in a cell-based model, was examined in hamsters. It was found that the compound does...
7.
Lin H, Rampersaud A, Richett M, Beavers L, McClure D, Gadski R
Steroids . 1998 May; 63(4):202-7. PMID: 9589554
4 alpha-(2-Propenyl)-5 alpha-cholestan-3 alpha-ol (LY295427) was previously identified from a CHO cell-based assay to be a potent LDL receptor up-regulator and had demonstrated to be an effective agent in lowering...
8.
Bowling N, Matter W, Gadski R, McClure D, Schreyer T, Dawson P, et al.
J Lipid Res . 1996 Dec; 37(12):2586-98. PMID: 9017510
LY295427, (3 alpha,4 alpha,5 alpha)-4-(2-propenylcholestan-3-ol), acts through an unknown mechanism to derepress the transcription of the low density lipoprotein (LDL) receptor in the presence of 25-hydroxycholesterol (25-OH chol). Preincubation with...
9.
Gehlert D, Beavers L, Johnson D, Gackenheimer S, Schober D, Gadski R
Mol Pharmacol . 1996 Feb; 49(2):224-8. PMID: 8632753
The 36-amino acid peptide, neuropeptide Y (NPY), is a member of a peptide family that includes the endocrine peptides, peptide YY (PYY), and pancreatic polypeptide (PP). NPY receptors have been...
10.
Lundell I, Blomqvist A, Berglund M, Schober D, Johnson D, Statnick M, et al.
J Biol Chem . 1995 Dec; 270(49):29123-8. PMID: 7493937
Neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP) are structurally related peptides found in all higher vertebrates. NPY is expressed exclusively in neurons, whereas PYY and PP are...