D B McClure
Overview
Explore the profile of D B McClure including associated specialties, affiliations and a list of published articles.
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35
Citations
347
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Recent Articles
1.
Li W, Butler J, Hale J, McClure D, Little S, Czilli D, et al.
Neuroscience
. 2000 Jan;
95(1):1-4.
PMID: 10619456
Secreted isoforms of the beta-amyloid precursor protein potently enhance neuronal survival in cell cultures exposed to toxic amyloid beta peptide. Lowering of intracellular calcium levels to offset the increases in...
2.
Lin H, Rampersaud A, Beavers L, McClure D, Gardner A, Eacho P, et al.
Steroids
. 1999 Sep;
64(10):735-41.
PMID: 10498032
4alpha-(2-Propenyl)-5alpha-cholest-24-en-3alpha-ol (3) was shown recently in a Chinese hamster ovary (CHO) cell-based low-density lipoprotein receptor/luciferase (LDLR/Luc) assay to be a potent transcriptional activator of the LDL receptor promoter in the...
3.
Lin H, Rampersaud A, Richett M, Harper R, Beavers L, McClure D, et al.
Steroids
. 1999 Jul;
64(3):217-27.
PMID: 10400383
4Alpha-(2-propenyl)-5alpha-cholestan-3alpha-ol (LY295427) was previously identified from a Chinese hamster ovary (CHO) cell-based low density lipoprotein receptor/luciferase (LDLR/Luc) assay to be a potent transcriptional activator of the LDL receptor promoter in...
4.
Bensch W, Gadski R, Bean J, Beavers L, Schmidt R, Perry D, et al.
J Pharmacol Exp Ther
. 1999 Mar;
289(1):85-92.
PMID: 10086991
The action of LY295427 [(3alpha,4alpha, 5alpha)-4-(2-propenylcholestan-3-ol)], a compound that derepresses low-density lipoprotein receptor (LDL-R) expression in a cell-based model, was examined in hamsters. It was found that the compound does...
5.
Lin H, Rampersaud A, Richett M, Beavers L, McClure D, Gadski R
Steroids
. 1998 May;
63(4):202-7.
PMID: 9589554
4 alpha-(2-Propenyl)-5 alpha-cholestan-3 alpha-ol (LY295427) was previously identified from a CHO cell-based assay to be a potent LDL receptor up-regulator and had demonstrated to be an effective agent in lowering...
6.
Bowling N, Matter W, Gadski R, McClure D, Schreyer T, Dawson P, et al.
J Lipid Res
. 1996 Dec;
37(12):2586-98.
PMID: 9017510
LY295427, (3 alpha,4 alpha,5 alpha)-4-(2-propenylcholestan-3-ol), acts through an unknown mechanism to derepress the transcription of the low density lipoprotein (LDL) receptor in the presence of 25-hydroxycholesterol (25-OH chol). Preincubation with...
7.
Berg D, McClure D, Grinnell B
Biotechniques
. 1993 Jun;
14(6):972-8.
PMID: 8333965
We have developed a host cell/vector system based on the use of adenovirus-transformed cells and a promoter, designated GBMT, capable of being activated by the Ela tumor antigen produced in...
8.
Peshwa M, Kyung Y, McClure D, Hu W
Biotechnol Bioeng
. 1993 Jan;
41(2):179-87.
PMID: 18609536
Recombinant human kidney epithelial 293 cells were cultivated as aggregates in suspension. The concentration calcium ion, in the range of 100 muM to 1mM, affected the rate of aggregate formation....
9.
Berg D, McClure D, Grinnell B
Nucleic Acids Res
. 1992 Oct;
20(20):5485-6.
PMID: 1437573
No abstract available.
10.
McClure D, Walls J, Grinnell B
J Biol Chem
. 1992 Sep;
267(27):19710-7.
PMID: 1527091
Human protein C (HPC) undergoes several post-translational modifications, including gamma-carboxylation, N-linked glycosylation, and internal proteolytic processing. We have utilized a recombinant human kidney cell line (293) secreting correctly modified HPC...