Qiu-Xing Jiang
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Explore the profile of Qiu-Xing Jiang including associated specialties, affiliations and a list of published articles.
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33
Citations
3013
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Recent Articles
1.
Yadav G, Annamalai M, Hagan D, Cui L, Mathews C, Jiang Q
bioRxiv
. 2025 Jan;
PMID: 39763853
Highlights: Loss of CHGB channel functions impairs secretory granule acidification in neuroendocrine cells, which necessitates anion shunt conduction. CHGBΔMIF, a mutant unable to form a functional Cl channel, exerts negative...
2.
Mugo A, Chou R, Chin F, Liu B, Jiang Q, Qin F
Proc Natl Acad Sci U S A
. 2023 Aug;
120(36):e2300305120.
PMID: 37639609
The vanilloid receptor TRPV1 is an exquisite nociceptive sensor of noxious heat, but its temperature-sensing mechanism is yet to define. Thermodynamics dictate that this channel must undergo an unusually energetic...
3.
Yadav G, Wang H, Ouwendijk J, Cross S, Wang Q, Qin F, et al.
Front Mol Neurosci
. 2023 Jul;
16:1205516.
PMID: 37435575
Regulated secretion is conserved in all eukaryotes. In vertebrates granin family proteins function in all key steps of regulated secretion. Phase separation and amyloid-based storage of proteins and small molecules...
4.
Jiang Q, Yadav G
Biochem Soc Trans
. 2022 Dec;
50(6):1659-1672.
PMID: 36511243
Chloride is the most abundant inorganic anions in almost all cells and in human circulation systems. Its homeostasis is therefore important for systems physiology and normal cellular activities. This topic...
5.
Zhou W, Yadav G, Yang X, Qin F, Li C, Jiang Q
Commun Biol
. 2022 Oct;
5(1):1054.
PMID: 36192627
Projected potential of 2.5-4.0 Å cryo-EM structures for structure-based drug design is not well realized yet. Here we show that a 3.1 Å structure of PRMT5 is suitable for selecting...
6.
Jiang Q
Adv Exp Med Biol
. 2021 Dec;
1371:109-129.
PMID: 34962637
Genome stability in eukaryotic cells relies on proper maintenance of telomeres at the termini of linear chromosomes. Human telomerase holoenzyme is required for maintaining telomere stability in a majority of...
7.
Jiang Q
Handb Exp Pharmacol
. 2021 Apr;
267:51-81.
PMID: 33829342
Potassium channels are present in every living cell and essential to setting up a stable, non-zero transmembrane electrostatic potential which manifests the off-equilibrium livelihood of the cell. They are involved...
8.
Sayed M, Cheng A, Yadav G, Ludlow A, Shay J, Wright W, et al.
J Biol Chem
. 2019 Jun;
294(30):11579-11596.
PMID: 31186347
Human telomerase maintains genome stability by adding telomeric repeats to the ends of linear chromosomes. Although previous studies have revealed profound insights into telomerase functions, the low cellular abundance of...
9.
Jiang Q
Adv Exp Med Biol
. 2019 Jan;
1115:167-190.
PMID: 30649760
Biomembranes separate a live cell from its environment and keep it in an off-equilibrium, steady state. They contain both phospholipids and nonphospholipids, depending on whether there are phosphate groups in...
10.
Jiang Q
Med Chem
. 2018 Dec;
15(5):443-458.
PMID: 30569868
Cells need high-sensitivity detection of non-self molecules in order to fight against pathogens. These cellular sensors are thus of significant importance to medicinal purposes, especially for treating novel emerging pathogens....