Qinzhe Wang
Overview
Explore the profile of Qinzhe Wang including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
209
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0
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Recent Articles
1.
Zhao Y, Shen J, Wang Q, Ruiz Munevar M, Vidossich P, De Vivo M, et al.
Proc Natl Acad Sci U S A
. 2022 Jun;
119(27):e2109083119.
PMID: 35759661
Cation-chloride cotransporters (CCCs) catalyze electroneutral symport of Cl with Na and/or K across membranes. CCCs are fundamental in cell volume homeostasis, transepithelia ion movement, maintenance of intracellular Cl concentration, and...
2.
Hussain M, Wang Q, Viola R
Arch Biochem Biophys
. 2021 Apr;
703:108870.
PMID: 33831357
Membrane-associated proteins carry out a wide range of essential cellular functions but the structural characterization needed to understand these functions is dramatically underrepresented in the Protein Data Bank. Producing a...
3.
Ha K, Nobuhara M, Wang Q, Walker R, Qian F, Schartner C, et al.
Elife
. 2020 Nov;
9.
PMID: 33164752
Mutations in the polycystin proteins, PC-1 and PC-2, result in autosomal dominant polycystic kidney disease (ADPKD) and ultimately renal failure. PC-1 and PC-2 enrich on primary cilia, where they are...
4.
Yang X, Wang Q, Cao E
Nat Commun
. 2020 May;
11(1):2359.
PMID: 32382061
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
5.
Yang X, Wang Q, Cao E
Nat Commun
. 2020 Feb;
11(1):1016.
PMID: 32081947
The secondary active cation-chloride cotransporters (CCCs) utilize the existing Na and/or K gradients to move Cl into or out of cells. NKCC1 is an intensively studied member of the CCC...
6.
Mutthamsetty V, Dahal G, Wang Q, Viola R
Chem Biol Drug Des
. 2019 Jul;
95(1):48-57.
PMID: 31260162
Canavan disease (CD) is a fatal leukodystrophy caused by mutations in the aspA gene coding for the enzyme aspartoacylase. Insufficient catalytic activity by this enzyme leads to the accumulation of...
7.
Parungao G, Zhao M, Wang Q, Zano S, Viola R, Blumenthal R
Microbiology (Reading)
. 2017 Nov;
163(12):1812-1821.
PMID: 29111970
S-adenosyl-l-methionine (AdoMet) is an essential metabolite, playing a wide variety of metabolic roles. The enzyme that produces AdoMet from l-methionine and ATP (methionine adenosyltransferase, MAT) is thus an attractive target...
8.
Thangavelu B, Mutthamsetty V, Wang Q, Viola R
Bioorg Med Chem
. 2016 Dec;
25(3):870-885.
PMID: 28007430
Canavan disease is a fatal neurological disorder caused by defects in the metabolism of N-acetyl-l-aspartate (NAA). Recent work has shown that the devastating symptoms of this disorder are correlated with...
9.
Coburn K, Wang Q, Rediske D, Viola R, Hanson B, Xue Z, et al.
Environ Sci Technol
. 2016 Jul;
50(17):9197-205.
PMID: 27366970
In our previous study, we reported that the transport of monochloramine is affected by the extracellular polymeric substance (EPS) composition, which in turn affects the cell viability of both biofilm...
10.
Wang Q, Zhao M, Parungao G, Viola R
Protein Expr Purif
. 2015 Nov;
119:11-8.
PMID: 26550943
Canavan disease (CD) is a neurological disorder caused by an interruption in the metabolism of N-acetylaspartate (NAA). Numerous mutations have been found in the enzyme that hydrolyzes NAA, and the...