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Qingdu Liu

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Articles 12
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Recent Articles
1.
Kobayashi H, Liu Q, Binns T, Urrutia A, Davidoff O, Kapitsinou P, et al.
J Clin Invest . 2016 Apr; 126(5):1926-38. PMID: 27088801
Renal peritubular interstitial fibroblast-like cells are critical for adult erythropoiesis, as they are the main source of erythropoietin (EPO). Hypoxia-inducible factor 2 (HIF-2) controls EPO synthesis in the kidney and...
2.
Farsijani N, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, et al.
J Clin Invest . 2016 Mar; 126(4):1425-37. PMID: 26927670
The adult kidney plays a central role in erythropoiesis and is the main source of erythropoietin (EPO), an oxygen-sensitive glycoprotein that is essential for red blood cell production. Decreases of...
3.
Liu Q, Davidoff O, Niss K, Haase V
J Clin Invest . 2012 Nov; 122(12):4635-44. PMID: 23114598
Iron demand in bone marrow increases when erythropoiesis is stimulated by hypoxia via increased erythropoietin (EPO) synthesis in kidney and liver. Hepcidin, a small polypeptide produced by hepatocytes, plays a...
4.
Kobayashi H, Gilbert V, Liu Q, Kapitsinou P, Unger T, Rha J, et al.
J Immunol . 2012 Apr; 188(10):5106-15. PMID: 22490864
Renal fibrosis and inflammation are associated with hypoxia, and tissue pO(2) plays a central role in modulating the progression of chronic kidney disease. Key mediators of cellular adaptation to hypoxia...
5.
Kapitsinou P, Liu Q, Unger T, Rha J, Davidoff O, Keith B, et al.
Blood . 2010 Jul; 116(16):3039-48. PMID: 20628150
The kidney is the main physiologic source of erythropoietin (EPO) in the adult and responds to decreases in tissue oxygenation with increased EPO production. Although studies in mice with liver-specific...
6.
Liu Q, Hirohashi Y, Du X, Greene M, Wang Q
Exp Mol Pathol . 2009 Dec; 88(2):225-33. PMID: 20034488
In mitosis, the duplicated chromosomes are separated and equally distributed to progeny cells under the guidance of the spindle, a dynamic microtubule network. Previous studies revealed a mitotic checkpoint that...
7.
Rankin E, Rha J, Selak M, Unger T, Keith B, Liu Q, et al.
Mol Cell Biol . 2009 Jun; 29(16):4527-38. PMID: 19528226
In mammals, the liver integrates nutrient uptake and delivery of carbohydrates and lipids to peripheral tissues to control overall energy balance. Hepatocytes maintain metabolic homeostasis by coordinating gene expression programs...
8.
Rankin E, Biju M, Liu Q, Unger T, Rha J, Johnson R, et al.
J Clin Invest . 2007 Apr; 117(4):1068-77. PMID: 17404621
Erythropoiesis is critically dependent on erythropoietin (EPO), a glycoprotein hormone that is regulated by hypoxia-inducible factor (HIF). Hepatocytes are the primary source of extrarenal EPO in the adult and express...
9.
Wang Q, Du X, Meinkoth J, Hirohashi Y, Zhang H, Liu Q, et al.
Proc Natl Acad Sci U S A . 2006 Apr; 103(17):6512-7. PMID: 16617106
The centrosome functions as the major microtubule-organizing center and plays a vital role in guiding chromosome segregation during mitosis. Centrosome abnormalities are frequently seen in a variety of cancers, suggesting...
10.
Zhao H, Wang Q, Zhang H, Liu Q, Du X, Richter M, et al.
Mol Biol Cell . 2005 Oct; 16(12):5857-65. PMID: 16221885
Ubiquitously expressed transcript (UXT) is a prefoldinlike protein that has been suggested to be involved in human tumorigenesis. Here, we have found that UXT is overexpressed in a number of...