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Qiangqiang He

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Articles 41
Citations 158
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Recent Articles
1.
He Q, Wei Y, Zhu H, Song Y, Chen P, Dong Q, et al.
J Nutr . 2024 Dec; 155(2):422-430. PMID: 39740751
Background: Polymorphisms of the folate-associated one-carbon metabolism (OCM) pathway genes may regulate certain susceptibilities to cancer. G80A, a polymorphism in the reduced folate carrier (RFC) gene, may be associated with...
2.
Siddiqi S, Liu L, Du Y, Song Y, Chen P, Li S, et al.
J Nutr . 2024 Sep; PMID: 39299473
Background: In China, the MTHFR 677T allele, unlike in most Western populations, is a rare genetic variant linked to various disorders. The contributing nutritional and genetic factors to this genetic...
3.
Qu M, He Q, Bao H, Ji X, Shen T, Barkat M, et al.
J Pharm Anal . 2024 Sep; 14(8):100957. PMID: 39253293
Arsenic compounds are widely used for the therapeutic intervention of multiple diseases. Ancient pharmacologists discovered the medicinal utility of these highly toxic substances, and modern pharmacologists have further recognized the...
4.
He Q, Qu M, Xu C, Wu L, Xu Y, Su J, et al.
Cancer Lett . 2024 May; 592:216922. PMID: 38704137
Lung adenocarcinoma (LUAD), a type of non-small cell lung cancer (NSCLC), originates from not only bronchial epithelial cells but also alveolar type 2 (AT2) cells, which could differentiate into AT2-like...
5.
He Q, Wei Y, Zhu H, Liang Q, Chen P, Li S, et al.
Discov Oncol . 2024 Apr; 15(1):97. PMID: 38565713
Background And Purpose: The enzyme methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in directing folate species towards nucleotide synthesis or DNA methylation. The MTHFR polymorphisms C677T and A1298C have been...
6.
He Q, Wei Y, Zhu H, Song Y, Chen P, Wang B, et al.
Curr Dev Nutr . 2024 Feb; 8(2):102075. PMID: 38351975
Background: The enzyme phosphatidylethanolamine N-methyltransferase () is responsible for synthesizing phosphatidylcholine by methylating phosphatidylethanolamine. We hypothesized that a polymorphism of the gene, rs7946, is involved in carcinogenesis. Objectives: We aimed...
7.
Zeng L, Tang C, Yao M, He Q, Qv M, Ren Q, et al.
Nat Commun . 2024 Feb; 15(1):987. PMID: 38307877
Aberrant activation of sonic hedgehog (SHH) signaling and its effector transcriptional factor GLI1 are essential for oncogenesis of SHH-dependent medulloblastoma (MB) and basal cell carcinoma (BCC). Here, we show that...
8.
Wei Y, He Q, Zhu H, Song Y, Liu L, Sun Y, et al.
J Nutr . 2023 Dec; 154(3):978-984. PMID: 38092150
Background: Previous studies have revealed that vitamin K is essential for preventing various chronic diseases. Phylloquinone is the primary dietary and circulating form of vitamin K. However, data concerning the...
9.
Wu J, Barkat M, Su J, Wu F, Tan D, Shen T, et al.
Biomed Pharmacother . 2023 Dec; 170:115986. PMID: 38056232
Infections like COVID-19 are the primary cause of death around the world because they can cause acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and sepsis. Inflammatory cells serve...
10.
Xu Y, Qu M, He Y, He Q, Shen T, Luo J, et al.
J Biol Chem . 2023 Oct; 299(12):105395. PMID: 37890777
Sterile 20-like kinases Mst1 and Mst2 (Mst1/2) and large tumor suppressor 1/2 are core kinases to mediate Hippo signaling in maintaining tissue homeostasis. We have previously demonstrated that Smad ubiquitin...