Priyadharshini Devarajan
Overview
Explore the profile of Priyadharshini Devarajan including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
366
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Recent Articles
1.
Devarajan P, Vong A, Castonguay C, Silverstein N, Kugler-Umana O, Bautista B, et al.
Cell Rep
. 2023 Nov;
42(11):113429.
PMID: 37934667
No abstract available.
2.
Devarajan P, Vong A, Castonguay C, Silverstein N, Kugler-Umana O, Bautista B, et al.
Cell Rep
. 2023 Sep;
42(10):113182.
PMID: 37776519
Cytotoxic CD4 T cell effectors (ThCTLs) kill virus-infected major histocompatibility complex (MHC) class II cells, contributing to viral clearance. We identify key factors by which influenza A virus infection drives...
3.
De Ana C, Shenoy A, Barker K, Arafa E, Etesami N, Korkmaz F, et al.
Mucosal Immunol
. 2023 Aug;
16(5):699-710.
PMID: 37604254
Streptococcus pneumoniae is the most common etiology of bacterial pneumonia, one of the leading causes of death in children and the elderly worldwide. During non-lethal infections with S. pneumoniae, lymphocytes...
4.
Jones M, Castonguay C, Nanaware P, Weaver G, Stadinski B, Kugler-Umana O, et al.
J Immunol
. 2023 Apr;
210(12):1950-1961.
PMID: 37093656
Initial TCR affinity for peptide Ag is known to impact the generation of memory; however, its contributions later, when effectors must again recognize Ag at 5-8 d postinfection to become...
5.
Iwanaga N, Devarajan P, Shenoy A
Front Immunol
. 2023 Mar;
14:1174178.
PMID: 36949940
No abstract available.
6.
Kugler-Umana O, Zhang W, Kuang Y, Liang J, Castonguay C, Tonkonogy S, et al.
Aging Cell
. 2022 Sep;
21(10):e13705.
PMID: 36056604
Age-associated B cells (ABC) accumulate with age and are associated with autoimmunity and chronic infection. However, their contributions to acute infection in the aged and their developmental pathways are unclear....
7.
Dhume K, Finn C, Devarajan P, Singh A, Tejero J, Prokop E, et al.
J Immunol
. 2022 Mar;
208(8):1998-2007.
PMID: 35338093
Optimal transcriptional programming needed for CD4 T cells to protect against influenza A virus (IAV) is unclear. Most IAV-primed CD4 T cells fit Th1 criteria. However, cells deficient for the...
8.
Devarajan P, Vong A, Castonguay C, Kugler-Umana O, Bautista B, Jones M, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(8).
PMID: 35177472
While influenza infection induces robust, long-lasting, antibody responses and protection, including the T follicular helper cells (T) required to drive B cell germinal center (GC) responses, most influenza vaccines do...
9.
Swain S, Jones M, Devarajan P, Xia J, Dutton R, Strutt T, et al.
Cold Spring Harb Perspect Biol
. 2021 Apr;
13(11).
PMID: 33903157
We have discovered that the determination of CD4 effector and memory fates after infection is regulated not only by initial signals from antigen and pathogen recognition, but also by a...
10.
Kugler-Umana O, Devarajan P, Swain S
Crit Rev Immunol
. 2021 Jan;
40(4):297-309.
PMID: 33426819
In humans and mice, susceptibility to infections and autoimmunity increases with age due to age-associated changes in innate and adaptive immune responses. Aged innate cells are also less active, leading...