Editorial: Adaptive Immunity to Respiratory Pathogens

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2023 Mar 23

PMID 36949940

Authors

Naoki Iwanaga

Priyadharshini Devarajan

Anukul T Shenoy

Affiliations

Soon will be listed here.

References

Pillai S . SARS-CoV-2 vaccination washes away original antigenic sin. Trends Immunol. 2022; 43(4):271-273. PMC: 8882427. DOI: 10.1016/j.it.2022.02.009. View

Shenoy A, De Ana C, Arafa E, Salwig I, Barker K, Korkmaz F . Antigen presentation by lung epithelial cells directs CD4 T cell function and regulates barrier immunity. Nat Commun. 2021; 12(1):5834. PMC: 8492657. DOI: 10.1038/s41467-021-26045-w. View

Devarajan P, Bautista B, Vong A, McKinstry K, Strutt T, Swain S . New Insights into the Generation of CD4 Memory May Shape Future Vaccine Strategies for Influenza. Front Immunol. 2016; 7:136. PMC: 4827017. DOI: 10.3389/fimmu.2016.00136. View

Barker K, Etesami N, Shenoy A, Arafa E, De Ana C, Smith N . Lung-resident memory B cells protect against bacterial pneumonia. J Clin Invest. 2021; 131(11). PMC: 8159694. DOI: 10.1172/JCI141810. View

Sathaliyawala T, Kubota M, Yudanin N, Turner D, Camp P, Thome J . Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity. 2012; 38(1):187-97. PMC: 3557604. DOI: 10.1016/j.immuni.2012.09.020. View

. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Infect Dis. 2018; 18(11):1191-1210. PMC: 6202443. DOI: 10.1016/S1473-3099(18)30310-4. View

Iwanaga N, Chen K, Yang H, Lu S, Hoffmann J, Wanek A . Vaccine-driven lung TRM cells provide immunity against via fibroblast IL-17R signaling. Sci Immunol. 2021; 6(63):eabf1198. PMC: 8796208. DOI: 10.1126/sciimmunol.abf1198. View

Wherry E, Barouch D . T cell immunity to COVID-19 vaccines. Science. 2022; 377(6608):821-822. DOI: 10.1126/science.add2897. View

Afkhami S, DAgostino M, Zhang A, Stacey H, Marzok A, Kang A . Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2. Cell. 2022; 185(5):896-915.e19. PMC: 8825346. DOI: 10.1016/j.cell.2022.02.005. View

10.

Allie S, Bradley J, Mudunuru U, Schultz M, Graf B, Lund F . The establishment of resident memory B cells in the lung requires local antigen encounter. Nat Immunol. 2018; 20(1):97-108. PMC: 6392030. DOI: 10.1038/s41590-018-0260-6. View

11.

Ndeupen S, Qin Z, Jacobsen S, Bouteau A, Estanbouli H, Igyarto B . The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory. iScience. 2021; 24(12):103479. PMC: 8604799. DOI: 10.1016/j.isci.2021.103479. View

12.

Amezcua Vesely M, Pallis P, Bielecki P, Low J, Zhao J, Harman C . Effector T17 Cells Give Rise to Long-Lived T Cells that Are Essential for an Immediate Response against Bacterial Infection. Cell. 2019; 178(5):1176-1188.e15. PMC: 7057720. DOI: 10.1016/j.cell.2019.07.032. View

13.

Tang J, Zeng C, Cox T, Li C, Son Y, Cheon I . Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination. Sci Immunol. 2022; 7(76):eadd4853. PMC: 9348751. DOI: 10.1126/sciimmunol.add4853. View

14.

Shenoy A, Wasserman G, Arafa E, Wooten A, Smith N, Martin I . Lung CD4 resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia. Mucosal Immunol. 2019; 13(2):334-343. PMC: 7044037. DOI: 10.1038/s41385-019-0229-2. View

15.

Pardi N, Hogan M, Naradikian M, Parkhouse K, Cain D, Jones L . Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. J Exp Med. 2018; 215(6):1571-1588. PMC: 5987916. DOI: 10.1084/jem.20171450. View

16.

Devarajan P, Vong A, Castonguay C, Kugler-Umana O, Bautista B, Jones M . Strong influenza-induced T generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection. Proc Natl Acad Sci U S A. 2022; 119(8). PMC: 8872786. DOI: 10.1073/pnas.2111064119. View

17.

Cupovic J, Ring S, Onder L, Colston J, Lutge M, Cheng H . Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells. Nat Immunol. 2021; 22(8):1042-1051. PMC: 7611414. DOI: 10.1038/s41590-021-00969-3. View

18.

Dunbar P, Cartwright E, Wein A, Tsukamoto T, Tiger Li Z, Kumar N . Pulmonary monocytes interact with effector T cells in the lung tissue to drive T differentiation following viral infection. Mucosal Immunol. 2019; 13(1):161-171. PMC: 6917844. DOI: 10.1038/s41385-019-0224-7. View