Preethi Krishnan
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Explore the profile of Preethi Krishnan including associated specialties, affiliations and a list of published articles.
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75
Citations
1612
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Recent Articles
1.
Krishnan P, Branco R, Weaver S, Chang G, Lee C, Syed F, et al.
J Biol Chem
. 2024 Sep;
300(11):107827.
PMID: 39342996
We previously showed that miR-146a-5p is upregulated in pancreatic islets treated with proinflammatory cytokines. Others have reported that miR-146a-5p overexpression is associated with β cell apoptosis and impaired insulin secretion....
2.
Krishnan P, Bobak C, Hill J
Sci Rep
. 2024 Jul;
14(1):16859.
PMID: 39039071
Confirmatory diagnosis of childhood tuberculosis (TB) remains a challenge mainly due to its dependence on sputum samples and the paucibacillary nature of the disease. Thus, only ~ 30% of suspected...
3.
Syed F, Ballew O, Lee C, Rana J, Krishnan P, Castela A, et al.
bioRxiv
. 2024 May;
PMID: 38766166
Tyrosine protein-kinase 2 (TYK2), a member of the Janus kinase family, mediates inflammatory signaling through multiple cytokines, including interferon-α (IFNα), interleukin (IL)-12, and IL-23. Missense mutations in TYK2 are associated...
4.
Krishnan P, Branco R, Weaver S, Chang G, Lee C, Syed F, et al.
bioRxiv
. 2024 Apr;
PMID: 38562689
We previously showed that miR-146a-5p is upregulated in pancreatic islets treated with pro-inflammatory cytokines. Others have reported that miR-146a-5p overexpression is associated with β cell apoptosis and impaired insulin secretion....
5.
Ideozu J, Liu M, Riley-Gillis B, Paladugu S, Rahimov F, Krishnan P, et al.
Genome Med
. 2024 Mar;
16(1):43.
PMID: 38515211
Background: Limited understanding of the diversity of variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene across ancestries hampers efforts to advance molecular diagnosis of cystic fibrosis (CF). The...
6.
Biswas M, So K, Bertolini T, Krishnan P, Rana J, Munoz-Melero M, et al.
Front Immunol
. 2023 Nov;
14:1278184.
PMID: 37954612
Oral administration of antigen induces regulatory T cells (Treg) that can not only control local immune responses in the small intestine, but also traffic to the central immune system to...
7.
Krishnan P, Rad M, Agarwal P, Marshall C, Yang P, Bhavani S, et al.
Physiol Meas
. 2023 Aug;
44(10).
PMID: 37652033
. To examine whether heart rate interval based rapid alert (HIRA) score derived from a combination model of heart rate variability (HRV) and modified early warning score (MEWS) is a...
8.
Iida H, Kono T, Lee C, Krishnan P, Arvin M, Weaver S, et al.
Diabetologia
. 2023 Aug;
66(11):2042-2061.
PMID: 37537395
Aims/hypothesis: Increased circulating levels of incompletely processed insulin (i.e. proinsulin) are observed clinically in type 1 and type 2 diabetes. Previous studies have suggested that Ca signalling within beta cells...
9.
Sohn P, McLaughlin M, Krishnan P, Wu W, Rupnik M, Takasu A, et al.
Diabetes
. 2023 Jul;
72(10):1433-1445.
PMID: 37478155
Article Highlights: Store-operated Ca2+ entry replenishes endoplasmic reticulum (ER) Ca2+ through reversible gating of plasma membrane Ca2+ channels by the ER Ca2+ sensor, stromal interaction molecule 1 (STIM1). β-Cell-specific deletion...
10.
Syed F, Krishnan P, Chang G, Langlais S, Hati S, Yamada K, et al.
bioRxiv
. 2023 Jul;
PMID: 37398133
MicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in modulating gene expression and are enriched in cell-derived extracellular vesicles (EVs). We investigated whether miRNAs from human islets...