Preethi Jayanth
Overview
Explore the profile of Preethi Jayanth including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
594
Followers
0
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Recent Articles
1.
Roma A, Tcheng M, Ahmed N, Walker S, Jayanth P, Minden M, et al.
Mol Cancer Res
. 2022 Aug;
20(11):1659-1673.
PMID: 35994381
Implications: This work highlights the effects of direct CII inhibition in mediating selective AML cell death and provides insights into glutamine anaplerosis as a metabolic adaptation that can be therapeutically...
2.
Tcheng M, Roma A, Ahmed N, Smith R, Jayanth P, Minden M, et al.
Blood
. 2021 Mar;
137(25):3518-3532.
PMID: 33720355
Acute myeloid leukemia (AML) cells have an atypical metabolic phenotype characterized by increased mitochondrial mass, as well as a greater reliance on oxidative phosphorylation and fatty acid oxidation (FAO) for...
3.
Ahmed N, Tcheng M, Roma A, Buraczynski M, Jayanth P, Rea K, et al.
Mol Nutr Food Res
. 2019 Oct;
63(24):e1900688.
PMID: 31609072
Scope: The effects of an avocado-derived fatty acid oxidation (FAO) inhibitor, avocatin B (AvoB), on glucose and lipid metabolism in models of diet-induced obesity (DIO) and in vitro models of...
4.
Ibrahim M, Mendis N, Roma A, Jayanth P, Minden M, Spagnuolo P
Leuk Lymphoma
. 2019 Jun;
60(12):3071-3074.
PMID: 31164029
No abstract available.
5.
Gilmour A, Abdulkhalek S, Cheng T, Alghamdi F, Jayanth P, OShea L, et al.
Cell Signal
. 2013 Sep;
25(12):2587-603.
PMID: 23993964
Epidermal growth factor (EGF)-induced EGFR tyrosine kinase receptor activation in cancer cell survival responses has become a strategic molecular-targeting clinical therapeutic intent, but the failures of these targeted approaches in...
6.
Mustafa F, Al Amri D, Al Ali F, Al Sari N, Al Suwaidi S, Jayanth P, et al.
PLoS One
. 2012 Oct;
7(10):e47088.
PMID: 23077548
Background: This study mapped regions of genomic RNA (gRNA) important for packaging and propagation of mouse mammary tumor virus (MMTV). MMTV is a type B betaretrovirus which preassembles intracellularly, a...
7.
Kulkarni R, Villanueva A, Elawadli I, Jayanth P, Read L, Haeryfar S, et al.
Cell Immunol
. 2012 Jul;
277(1-2):33-43.
PMID: 22795895
Invariant NKT (iNKT) cells are glycolipid-reactive lymphocytes with anti-microbial properties. Toll-like receptor (TLR)-primed antigen-presenting cells are known to activate iNKT cells, however, the expression and function of TLRs in iNKT...
8.
Abdulkhalek S, Guo M, Amith S, Jayanth P, Szewczuk M
Cell Signal
. 2012 Jul;
24(11):2035-42.
PMID: 22759791
The mechanism(s) behind GPCR transactivation of TLR receptors independent of TLR ligands is unknown. Here, GPCR agonists bombesin, bradykinin, lysophosphatidic acid (LPA), cholesterol, angiotensin-1 and -2, but not thrombin induce...
9.
Abdulkhalek S, Amith S, Franchuk S, Jayanth P, Guo M, Finlay T, et al.
J Biol Chem
. 2011 Aug;
286(42):36532-49.
PMID: 21873432
The signaling pathways of mammalian Toll-like receptors (TLRs) are well characterized, but the precise mechanism(s) by which TLRs are activated upon ligand binding remains poorly defined. Recently, we reported a...
10.
Amith S, Jayanth P, Finlay T, Franchuk S, Gilmour A, Abdulkhalek S, et al.
J Vis Exp
. 2010 Sep;
(43).
PMID: 20864924
Mammalian Toll-like receptors (TLRs) are a family of receptors that recognize pathogen-associated molecular patterns. Not only are TLRs crucial sensors of microbial (e.g., viruses, bacteria and parasite) infections, they also...