Pragati Singh
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Explore the profile of Pragati Singh including associated specialties, affiliations and a list of published articles.
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25
Citations
136
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Recent Articles
1.
Singh P, Reza M, Syed A, Husain A, Gayen J
Biochimie
. 2023 Jun;
214(Pt B):114-122.
PMID: 37364770
Hepatic steatosis is an important mstetabolic complication in women encountering postmenopausal phase of life. Pancreastatin (PST), has previously been investigated in diabetic and insulin resistant rodents. The present study highlighted...
2.
Syed A, Reza M, Kalleti N, Husain A, Singh P, Rath S, et al.
Toxicology
. 2022 Nov;
483:153373.
PMID: 36370889
Recent studies have focused on exploring the efficacy of Cissus quadrangularis extract (EECQ) against various metabolic disorders involving the liver as the prime target organ, suggesting a considerable threat of...
3.
Singh P, Ishteyaque S, Prajapati R, Yadav K, Singh R, Kumar A, et al.
Hum Exp Toxicol
. 2022 Jan;
41:9603271211061873.
PMID: 35072544
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by chronic hyperglycemia and insulin resistance. 4-hydroxyisoleucine (4-HIL) is a non-proteinogenic amino acid isolated from the fenugreek seeds and has...
4.
Syed A, Reza M, Singh P, Husain A, Dadge S, Gayen J
Exp Gerontol
. 2022 Jan;
159:111681.
PMID: 34973346
Insulin resistance (IR) is a significant complication in menopausal women, which predisposes them to cardiovascular disorder, obesity, and diabetes. Cissus quadrangularis is a polyphenolic plant rich in nutrients and is...
5.
Katekar R, Singh P, Garg R, Verma S, Gayen J
Pharm Dev Technol
. 2021 Nov;
27(1):95-107.
PMID: 34806547
'One drug- one target' to 'multiple drug- multiple targets' paradigm shifted to produce combination therapies, have found great outcomes to overcome multiple drug resistance (MDR). MDR is a significant barrier...
6.
Syed A, Shafiq M, Reza M, Bharati P, Husain A, Singh P, et al.
Clin Exp Hypertens
. 2021 Oct;
44(1):63-71.
PMID: 34648416
Background: Endothelial dysfunction is related to the reduced bioavailability of nitric oxide (NO) and plays a significant role in developing hypertension. The intake of a diet rich in antioxidants decreases...
7.
Reza M, Syed A, Singh P, Husain A, Gayen J
Life Sci
. 2021 Aug;
284:119905.
PMID: 34453940
Aims: Mitochondrial dysfunction is among the key factors for the advancement of hepatic steatosis to NAFLD and NASH. Pancreastatin (PST: human ChgA250-301) is a dysglycemic hormone, previously reported to promote...
8.
Singal S, Sikdar S, Kaushik S, Singh P, Bhatt N, Samandari G, et al.
Sex Reprod Health Matters
. 2021 Jun;
29(2):1-16.
PMID: 34148520
The Government of India has promoted the expansion of access to and uptake of intrauterine devices (IUDs), during both the interval (IIUD) and postpartum (PPIUD) periods, as part of its...
9.
Singh P, Reza M, Syed A, Husain A, Katekar R, Gayen J
Life Sci
. 2021 Jun;
279:119677.
PMID: 34081990
Aims: Pancreastatin (PST) is a crucial bioactive peptide derived from chromogranin A (CHGA) proprotein that exhibits an anti-insulin effect on adipocytes. Herein, we investigated the effects of PST on brown...
10.
Dixit V, Singh P
In Silico Pharmacol
. 2021 May;
9(1):37.
PMID: 34017677
Toxicity related failures in drug discovery and clinical development have motivated scientists and regulators to develop a wide range of in-vitro, in-silico tools coupled with data science methods. Older drug...