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Pharmaceutical Development and Technology

Pharmaceutical Development and Technology is a reputable journal that focuses on the latest advancements in the field of pharmaceutical development. It covers a wide range of topics including drug formulation, delivery systems, process optimization, and quality control. With its rigorous peer-review process, the journal provides valuable insights and research findings to professionals and researchers in the pharmaceutical industry.
Details
Abbr. Pharm Dev Technol
Publisher Informa Healthcare
Start 1996
End Continuing
Frequency Quarterly
p-ISSN 1083-7450
e-ISSN 1097-9867
Country United Kingdom
Language English
Specialties Pharmacology
Pharmacy
Metrics
h-index / Ranks: 5130 70
SJR / Ranks: 9262 476
CiteScore / Ranks: 3723 6.10
JIF / Ranks: 2884 3.4
Recent Articles
1.
Exploring the Application of Single-step Drying in Lyophilization of High Protein Concentration Formulations
Zeng Q, Jin Z, Guo J
Pharm Dev Technol . 2025 Mar; :1-13. PMID: 40084425
Single-step drying integrates sublimation and desorption process in one step. Here, single-step drying was proved to be applicable to formulations with or without viscosity reducers among high protein concentration lyophilization...
2.
Assessment of therapeutic effectiveness of developed colchicine transnovasomes in treatment of recurrent aphthous ulcer as monotherapy and combination therapy with platelet-rich plasma
Kandil S, Soliman I, Hosni M, Salama A, Abdou E
Pharm Dev Technol . 2025 Mar; :1-19. PMID: 40052372
Objectives: Transnovasomes is a new exciting class of lipid-based nanovesicles. Colchicine (COL) is a hydrophilic natural alkaloid with anti-inflammatory features having oral administration and permeation defects. Recurrent Aphthous Ulcer (RAU)...
3.
Insight into manufacturing of bespoke combination drug products containing carvedilol and simvastatin by fused deposition modeling
Korsgaard Andreasen L, KorsgaardAndreasen L, Slot Andreasen E, SlotAndreasen E, He W, Rantanen J, et al.
Pharm Dev Technol . 2025 Mar; :1-9. PMID: 40035789
The goal of this study was to explore the fabrication of a combination drug product containing two poorly soluble active pharmaceutical ingredients (APIs), carvedilol (CAR) and simvastatin (SIM), in therapeutically...
4.
Preparation and characterization of immediate release 3D printed tablets using hot melt extruded amorphous cyclosporine a filament
Jeong J, Han C, Kang J, Yoo K, Jung W, Park Y, et al.
Pharm Dev Technol . 2025 Mar; :1-11. PMID: 40024886
3D printing technology is gaining attention as a next-generation approach to drug formulation. Among 3D printing techniques, fused deposition modeling is cost-effective but depends heavily on suitable filaments. Hot melt...
5.
Preparation of diltiazem HCl-modified release formulation using cation-exchange resin as a single excipient
Alkhamis K, Al-Nimry S
Pharm Dev Technol . 2025 Feb; :1-8. PMID: 40019464
Objective: Modified released formulations of diltiazem were previously prepared using cation-exchange resins. However, multiple excipients were required to achieve the appropriate release rate. It was of interest to prepare a...
6.
-derived vesicles loaded with dextromethorphan as a candidate for the management of neuroinflammation related to Alzheimer's disease
Valizadeh P, Mozafari N, Ashrafi H, Heidari R, Azarpira N, Azadi A
Pharm Dev Technol . 2025 Feb; :1-9. PMID: 40014618
Alzheimer's disease (AD) is a neurodegenerative disease that is associated with neuroinflammation. Dextromethorphan (DXM) exerts neuroprotective effects in many central nervous system injuries and neurodegenerative diseases. The cell wall of...
7.
Engineering orally disintegrating tablets for buccal delivery of cilostazol with enhanced dissolution and bioavailability: a novel dual porogenic approach, characterization, and evaluation in rats
Fouad S, Abdelaziz N, Teaima M, El-Nabarawi M, Taha A, Abdelmonem R, et al.
Pharm Dev Technol . 2025 Feb; :1-15. PMID: 40007241
Cilostazol (CTZ), is a BCS class II drug with limited bioavailability. In the current study, orally disintegrating tablets (ODTs) for buccal delivery of CTZ were prepared by two methods; lyophilization...
8.
Ezetimibe Oral Solid Lipid Nanoparticle by Effervescent Dispersion Method: Characterization And Pharmacokinetic Study in Rats
Darweesh R, AlQawasmi F, Khanfar M
Pharm Dev Technol . 2025 Feb; :1-36. PMID: 39989184
Ezetimibe (EZT) is a class II drug of the Biopharmaceutics classification system (BCS), with limited aqueous solubility and high permeability. This study aims to enhance the solubility and oral bioavailability...
9.
Ocular polymeric nanomicelles for the posterior eye segment in the management of retinoblastoma: formulation, optimization, and evaluations
Ansari M, Kulkarni Y, Singh K
Pharm Dev Technol . 2025 Feb; :1-13. PMID: 39985152
The existing study focuses on the development, optimization, and evaluation of sorafenib-loaded polymeric nanomicelles for posterior segment delivery in treating retinoblastoma. The formulation involved adjusting various process and product parameters...
10.
Formulation and optimization of glycyrrhetinic acid-modified pH-sensitive curcumin liposomes for anti-hepatocellular carcinoma
Wang J, Gu X, Gao X, Chen J, Lv Z, Zhang S, et al.
Pharm Dev Technol . 2025 Feb; :1-13. PMID: 39935270
In order to enhance the therapeutic value of curcumin in liver cancer treatment, glycyrrhetinic acid-modified pH-sensitive curcumin liposomes (GA-pH-Lip@Cur) was developed.GA-pH-Lip@Cur was prepared using a thin film dispersion ultrasonication method,...