Anand P Gupta
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Explore the profile of Anand P Gupta including associated specialties, affiliations and a list of published articles.
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26
Citations
204
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Recent Articles
1.
Goand U, Verma S, Gupta A, Garg R, Dadge S, Gayen J
Peptides
. 2022 Nov;
159:170902.
PMID: 36375661
Pancreastatin (PST) is an endogenous bioactive peptide. PST is generated from chromogranin A (Chga) protein which is released by chromaffin and neuroendocrine cells. PST exhibits diabetogenic effect by antagonizing the...
2.
Garg R, Gupta A, Katekar R, Verma S, Goand U, Dadge S, et al.
Life Sci
. 2021 Dec;
289:120221.
PMID: 34902437
Aim: Free fatty acid-mediated obesity plays a crucial role in the pathogenesis of Type 2 Diabetes. FFA induced JNK activation acts as a central regulator in causing hepatic insulin resistance....
3.
Gupta J, Singh D, Verma P, Rahuja N, Srivastava R, Ahmad I, et al.
Pharmacology
. 2021 Nov;
107(1-2):54-68.
PMID: 34814141
Introduction: The present study deals with the synthesis of pregnane-oximino-amino-alkyl-ethers and their evaluation for antidiabetic and anti-dyslipidemic activities in validated animal and cell culture models. Methods: The effect on glucose...
4.
Singh P, Reza M, Syed A, Garg R, Husain A, Katekar R, et al.
Heliyon
. 2021 Jan;
6(12):e05826.
PMID: 33426334
Aims: Hepatic steatosis in women confronting menopause is the manifestation of substantial fructose consumption and forms a positive feedback loop to develop endoplasmic reticulum (ER) stress. Previously pancreastatin inhibitor peptide-8...
5.
Singh P, Garg R, Goand U, Riyazuddin M, Reza M, Syed A, et al.
Heliyon
. 2020 Oct;
6(10):e05133.
PMID: 33033766
In the preceding study, we delineated that high-fat diet (HFD) consumption in mice increases the circulatory level of pancreastatin (PST), which additionally enhances the free fatty acid (FFA) concentration in...
6.
Gupta A, Garg R, Singh P, Goand U, Syed A, Valicherla G, et al.
Eur J Pharmacol
. 2020 May;
881:173204.
PMID: 32439261
Pancreastatin (PST), a chromogranin A (CHGA) derived peptide connects obesity with insulin resistance by inducing inflammation. Previously, we have evaluated potential activity of PST inhibitor (PSTi8) in liver and adipose...
7.
Valicherla G, Riyazuddin M, Shahi S, Gupta A, Syed A, Husain A, et al.
J Pharm Biomed Anal
. 2020 Jan;
180:113074.
PMID: 31891874
PSTi8 is a 21 amino acid pancreastatin inhibitory peptide that demonstrated potent antidiabetic activity in insulin resistant rodent models. The goal of the current work is to establish and validate...
8.
Riyazuddin M, Husain A, Valicherla G, Verma S, Gupta A, Praveena K, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2019 Nov;
1130-1131:121829.
PMID: 31670104
S011-2111 is a semicarbazone and chalcone hybrid demonstrating antiproliferative tumor cell-selective effects along with unique antimetastatic potential by mitigating PP2A-β-catenin signalling pathway. The present study envisaged to explore the in...
9.
Gupta A, Syed A, Garg R, Goand U, Singh P, Riyazuddin M, et al.
Eur J Pharmacol
. 2019 Oct;
864:172723.
PMID: 31586632
Pancreastatin (PST), a chromogranin A derived peptide has anti-insulin effects and plays a significant role in obesity-induced insulin resistance. In obesity and type 2 diabetes mellitus, both insulin and PST...
10.
Valicherla G, Gupta A, Hossain Z, Riyazuddin M, Syed A, Husain A, et al.
Peptides
. 2019 Sep;
120:170147.
PMID: 31473204
Increase in the prevalence of insulin resistance (IR) in peri-/post-menopause women is mainly due to hormone deficiency and lifestyle. PSTi8 (PEGKGEQEHSQQKEEEEEMAV-amide) is a pancreastatin inhibitor peptide which showed potent antidiabetic...