Ponnusamy Kalaiarasan
Overview
Explore the profile of Ponnusamy Kalaiarasan including associated specialties, affiliations and a list of published articles.
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19
Citations
215
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Recent Articles
11.
Nafis S, Kalaiarasan P, Brojen Singh R, Husain M, Bamezai R
Brief Bioinform
. 2014 Sep;
16(4):675-99.
PMID: 25256288
Dysregulation or inhibition of apoptosis favors cancer and many other diseases. Understanding of the network interaction of the genes involved in apoptotic pathway, therefore, is essential, to look for targets...
12.
Kalaiarasan P, Subbarao N, Bamezai R
J Mol Model
. 2014 Sep;
20(9):2447.
PMID: 25208557
Tyrosine phosphorylation (p-Y105) of pyruvate kinase (PK) M2, in recent years, has been suggested to facilitate Warburg effect and tumor cell growth. However, a comparison of the structural dynamics of...
13.
Chopra R, Kalaiarasan P, Ali S, Srivastava A, Aggarwal S, Garg V, et al.
BMJ Open
. 2014 Mar;
4(2):e004239.
PMID: 24578538
Objectives: Cytokines and related molecules in immune-response pathways seem important in deciding the outcome of the host-pathogen interactions towards different polar forms in leprosy. We studied the role of significant...
14.
Chopra R, Ali S, Srivastava A, Aggarwal S, Kumar B, Manvati S, et al.
PLoS Genet
. 2013 Jul;
9(7):e1003578.
PMID: 23861666
Leprosy is a chronic infectious disease caused by Mycobacterium Leprae, where the host genetic background plays an important role toward the disease pathogenesis. Various studies have identified a number of...
15.
Danishuddin M, Khan A, Faheem M, Kalaiarasan P, Baig M, Subbarao N, et al.
J Biomol Struct Dyn
. 2013 Apr;
32(5):741-50.
PMID: 23600675
KPC-2 β-lactamase demonstrates a wide substrate spectrum that includes carbapenamases, oxyimino-cephalosporins, and cephamycins. In addition, strains harboring KPC-type β-lactamases are often identified as resistant to standard β-lactamase inhibitors. Thus, KPC-2...
16.
Ali S, Chopra R, Aggarwal S, Srivastava A, Kalaiarasan P, Malhotra D, et al.
Hum Genet
. 2011 Nov;
131(5):703-16.
PMID: 22071774
Host immune response against Mycobacterium leprae plays an important role in providing resistance to infection and disease progression. Genome-wide linkage and association studies suggest the possibility of multiple risk loci...
17.
Aggarwal S, Ali S, Chopra R, Srivastava A, Kalaiarasan P, Malhotra D, et al.
J Infect Dis
. 2011 Sep;
204(8):1264-73.
PMID: 21917900
Background: Mycobacterium leprae is the etiologic pathogen that causes leprosy. The outcome of disease is dependent on the host genetic background. Methods: We investigated the association of 51 single-nucelotide polymorphisms...
18.
Srivastava N, Manvati S, Srivastava A, Pal R, Kalaiarasan P, Chattopadhyay S, et al.
Breast Cancer Res
. 2011 Apr;
13(2):R39.
PMID: 21463514
Introduction: New levels of gene regulation with microRNA (miR) and gene copy number alterations (CNAs) have been identified as playing a role in various cancers. We have previously reported that...
19.
Gupta V, Kalaiarasan P, Faheem M, Singh N, Iqbal M, Bamezai R
J Biol Chem
. 2010 Mar;
285(22):16864-73.
PMID: 20304929
This study was designed to understand the mechanism and functional implication of the two heterozygous mutations (H391Y and K422R) of human pyruvate kinase M2 isozyme (PKM(2)) observed earlier in a...