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Rupali Chopra

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Articles 21
Citations 306
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Recent Articles
1.
Girardi L, Serdarogullari M, Patassini C, Poli M, Fabiani M, Caroselli S, et al.
Am J Hum Genet . 2020 Mar; 106(4):525-534. PMID: 32220293
Despite next-generation sequencing, which now allows for the accurate detection of segmental aneuploidies from in vitro fertilization embryo biopsies, the origin and characteristics of these aneuploidies are still relatively unknown....
2.
Manvati S, Mangalhara K, Kalaiarasan P, Chopra R, Agarwal G, Kumar R, et al.
Cancer Cell Int . 2019 Sep; 19:230. PMID: 31516387
Background: Despite several reports describing the dual role of miR-145 as an oncogene and a tumor suppressor in cancer, not much has been resolved and understood. Method: In this study,...
3.
Linan A, Lawrenz B, El Khatib I, Bayram A, Arnanz A, Rubio C, et al.
PLoS One . 2018 Aug; 13(8):e0201652. PMID: 30133476
One of the most important limitations of genetic testing in preimplantation embryos is embryonic mosaicism, especially when performed on D3 with only a single blastomere evaluated. Previous publications, using Array-Comparative...
4.
Baldev V, Chopra R, Batra N, Singh S
J Clin Diagn Res . 2017 Oct; 11(8):NC20-NC23. PMID: 28969173
Introduction: The frequency of eye diseases has been suggested to start increasing around 40 years of age, with an even steeper increase beginning around 60 years of age. Health promotions...
5.
Kalaiarasan P, Kumar B, Chopra R, Gupta V, Subbarao N, Bamezai R
PLoS One . 2015 Mar; 10(3):e0120469. PMID: 25768091
Role of, 29-non-synonymous, 15-intronic, 3-close to UTR, single nucleotide polymorphisms (SNPs) and 2 mutations of Human Pyruvate Kinase (PK) M2 were investigated by in-silico and in-vitro functional studies. Prediction of...
6.
Singh R, Srivastava A, Kalaiarasan P, Manvati S, Chopra R, Bamezai R
Sci Rep . 2014 Oct; 4:6571. PMID: 25300428
mtDNA non-synonymous germ line variation (G10398A; p.A114T) has remained equivocal with least mechanistic understanding in showing an association with cancer. This has necessitated showing in-vitro how an over-expression within mitochondria...
7.
Srivastava A, Chopra R, Ali S, Aggarwal S, Vig L, Bamezai R
Nucleic Acids Res . 2014 Jul; 42(15):e122. PMID: 25030906
Inundation of evolutionary markers expedited in Human Genome Project and 1000 Genome Consortium has necessitated pruning of redundant and dependent variables. Various computational tools based on machine-learning and data-mining methods...
8.
Chopra R, Kalaiarasan P, Ali S, Srivastava A, Aggarwal S, Garg V, et al.
BMJ Open . 2014 Mar; 4(2):e004239. PMID: 24578538
Objectives: Cytokines and related molecules in immune-response pathways seem important in deciding the outcome of the host-pathogen interactions towards different polar forms in leprosy. We studied the role of significant...
9.
Chopra R, Ali S, Srivastava A, Aggarwal S, Kumar B, Manvati S, et al.
PLoS Genet . 2013 Jul; 9(7):e1003578. PMID: 23861666
Leprosy is a chronic infectious disease caused by Mycobacterium Leprae, where the host genetic background plays an important role toward the disease pathogenesis. Various studies have identified a number of...
10.
Ali S, Chopra R, Manvati S, Singh Y, Kaul N, Behura A, et al.
PLoS One . 2013 Mar; 8(3):e58881. PMID: 23527042
Type 2 diabetes (T2D) is a syndrome of multiple metabolic disorders and is genetically heterogeneous. India comprises one of the largest global populations with highest number of reported type 2...