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Pitchaimani Kandasamy

Explore the profile of Pitchaimani Kandasamy including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 371
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Recent Articles
1.
Numata M, Kandasamy P, Voelker D
Immunol Rev . 2023 May; 317(1):166-186. PMID: 37144896
The pulmonary surfactant system of the lung is a lipid and protein complex, which regulates the biophysical properties of the alveoli to prevent lung collapse and the innate immune system...
2.
Numata M, Mitchell J, Tipper J, Brand J, Trombley J, Nagashima Y, et al.
J Biol Chem . 2019 Dec; 295(6):1704-1715. PMID: 31882535
The influenza A (H1N1)pdm09 outbreak in 2009 exemplified the problems accompanying the emergence of novel influenza A virus (IAV) strains and their unanticipated virulence in populations with no pre-existing immunity....
3.
Honda J, Hess T, Carlson R, Kandasamy P, Nieto Ramirez L, Norton G, et al.
Am J Respir Cell Mol Biol . 2019 Sep; 62(3):354-363. PMID: 31545652
Comparisons of infectivity among the clinically important nontuberculous mycobacteria (NTM) species have not been explored in great depth. Rapid-growing mycobacteria, including and , can cause indolent but progressive lung disease....
4.
Kandasamy P, Numata M, Zemski Berry K, Fickes R, Leslie C, Murphy R, et al.
J Lipid Res . 2016 Apr; 57(6):993-1005. PMID: 27095543
The pulmonary surfactant phospholipid, 1-palmitoyl-2-oleoylphosphatidylglycerol (POPG), potently inhibits toll-like receptor (TLR)2 and TLR4 signaling from the cell surface of macrophages. Analogs of POPG that vary in polar head group length,...
5.
Numata M, Kandasamy P, Nagashima Y, Fickes R, Murphy R, Voelker D
J Lipid Res . 2015 Jan; 56(3):578-587. PMID: 25561461
Respiratory syncytial virus (RSV) infects nearly all children under age 2, and reinfection occurs throughout life, seriously impacting adults with chronic pulmonary diseases. Recent data demonstrate that the anionic pulmonary...
6.
Ning F, Wang C, Zemski Berry K, Kandasamy P, Liu H, Murphy R, et al.
FASEB J . 2014 Sep; 28(12):5349-60. PMID: 25223608
The short palate, lung and nasal epithelial clone 1 (SPLUNC1) protein is a member of the palate, lung, and nasal epithelium clone (PLUNC) family, also known as bactericidal/permeability-increasing (BPI) fold-containing...
7.
Numata M, Nagashima Y, Moore M, Berry K, Chan M, Kandasamy P, et al.
J Lipid Res . 2013 Jun; 54(8):2133-2143. PMID: 23749985
Respiratory syncytial virus (RSV) causes respiratory tract infections in young children, and significant morbidity and mortality in the elderly, immunosuppressed, and immunocompromised patients and in patients with chronic lung diseases....
8.
Numata M, Kandasamy P, Voelker D
Expert Rev Respir Med . 2012 Jul; 6(3):243-6. PMID: 22788936
No abstract available.
9.
Numata M, Kandasamy P, Nagashima Y, Posey J, Hartshorn K, Woodland D, et al.
Am J Respir Cell Mol Biol . 2011 Nov; 46(4):479-87. PMID: 22052877
Influenza A virus (IAV) is a worldwide public health problem causing 500,000 deaths each year. Palmitoyl-oleoyl-phosphatidylglycerol (POPG) is a minor component of pulmonary surfactant, which has recently been reported to...
10.
Wang Y, Voelker D, Lugogo N, Wang G, Floros J, Ingram J, et al.
Am J Physiol Lung Cell Mol Physiol . 2011 Jul; 301(4):L598-606. PMID: 21784968
Surfactant protein A (SP-A) regulates a variety of immune cell functions. We determined the ability of SP-A derived from normal and asthmatic subjects to modulate the inflammatory response elicited by...