» Authors » Dennis R Voelker

Dennis R Voelker

Explore the profile of Dennis R Voelker including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 115
Citations 6044
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Tanyaratsrisakul S, Bochkov Y, White V, Lee H, Loeffler J, Everman J, et al.
Viruses . 2024 Nov; 16(11. PMID: 39599822
Rhinovirus C (RV-C) infection can trigger asthma exacerbations in children and adults, and RV-C-induced wheezing illnesses in preschool children correlate with the development of childhood asthma. Surfactant protein A (SP-A)...
2.
Gross R, Ressin H, von Maltitz P, Albers D, Schneider L, Bley H, et al.
Nat Microbiol . 2024 Mar; 9(4):905-921. PMID: 38528146
Some viruses are rarely transmitted orally or sexually despite their presence in saliva, breast milk, or semen. We previously identified that extracellular vesicles (EVs) in semen and saliva inhibit Zika...
3.
Numata M, Kandasamy P, Voelker D
Immunol Rev . 2023 May; 317(1):166-186. PMID: 37144896
The pulmonary surfactant system of the lung is a lipid and protein complex, which regulates the biophysical properties of the alveoli to prevent lung collapse and the innate immune system...
4.
Choi J, Lopes L, Ben Mamoun C, Voelker D
J Biol Chem . 2023 Mar; 299(5):104659. PMID: 36997087
Decarboxylation of phosphatidylserine (PS) to form phosphatidylethanolamine by PS decarboxylases (PSDs) is an essential process in most eukaryotes. Processing of a malarial PSD proenzyme into its active alpha and beta...
5.
Numata M, Sajuthi S, Bochkov Y, Loeffler J, Everman J, Vladar E, et al.
Viruses . 2023 Mar; 15(3). PMID: 36992456
Rhinoviruses (RVs) are major instigators of acute exacerbations of asthma, COPD, and other respiratory diseases. RVs are categorized into three species (RV-A, RV-B, and RV-C), which comprise more than 160...
6.
Francisco D, Wang Y, Marshall C, Conway M, Addison K, Billheimer D, et al.
Front Immunol . 2022 Jul; 13:900022. PMID: 35874703
Surfactant Protein-A (SP-A) is an innate immune modulator that regulates a variety of pulmonary host defense functions. We have shown that SP-A is dysfunctional in asthma, which could be partly...
7.
Numata M, Voelker D
Biochim Biophys Acta Mol Cell Biol Lipids . 2022 Mar; 1867(6):159139. PMID: 35240310
Pulmonary surfactant is a mixture of lipids and proteins, consisting of 90% phospholipid, and 10% protein by weight, found predominantly in pulmonary alveoli of vertebrate lungs. Two minor components of...
8.
Rizzo A, Haeger S, Oshima K, Yang Y, Wallbank A, Jin Y, et al.
JCI Insight . 2021 Dec; 7(2). PMID: 34874923
Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure yet has few pharmacologic therapies, reflecting the mechanistic heterogeneity of lung injury. We hypothesized that damage to the...
9.
Garcia J, Schwabe M, Voelker D, Riekhof W
G3 (Bethesda) . 2021 Sep; 11(10). PMID: 34568930
The alkylphosphocholine (APC) class of antineoplastic and antiprotozoal drugs, such as edelfosine and miltefosine, are structural mimics of lyso-phosphatidylcholine (lyso-PC), and are inhibitory to the yeast Saccharomyces cerevisiae at low...
10.
Choi J, Black 3rd R, Lee H, Di Giovanni J, Murphy R, Ben Mamoun C, et al.
J Biol Chem . 2020 May; 295(27):9211-9222. PMID: 32430397
Phosphatidylserine decarboxylases (PSDs) catalyze the conversion of phosphatidylserine (PS) to phosphatidylethanolamine (PE), a critical step in membrane biogenesis and a potential target for development of antimicrobial and anti-cancer drugs. PSD...