Pieter Johan Adam Eichhorn
Overview
Explore the profile of Pieter Johan Adam Eichhorn including associated specialties, affiliations and a list of published articles.
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19
Citations
415
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Recent Articles
1.
Chan A, Gill J, Chih H, Wright S, Vasilevski N, Eichhorn P
JCO Precis Oncol
. 2024 Dec;
8:e2400274.
PMID: 39642326
Purpose: The presence of epithelial-mesenchymal transition (EMT) in breast cancer (BC) cells has been linked to worse prognosis and may influence response to systemic treatment. We explored the effect of...
2.
Li B, Eichhorn P, Chng W
Cancer Lett
. 2024 May;
594:216978.
PMID: 38795760
Ubiquitination and related cellular processes control a variety of aspects in human cell biology, and defects in these processes contribute to multiple illnesses. In recent decades, our knowledge about the...
3.
Lai X, Lui S, Lam H, Adachi Y, Sim W, Vasilevski N, et al.
NPJ Precis Oncol
. 2023 Dec;
7(1):136.
PMID: 38102334
Despite the promising antitumor activity of SHP2 inhibitors in RAS-dependent tumours, overall responses have been limited by their narrow therapeutic window. Like with all MAPK pathway inhibitors, this is likely...
4.
Wang X, Eichhorn P, Thiery J
Semin Cancer Biol
. 2023 Nov;
97:1-11.
PMID: 37944215
Transforming growth factor-β (TGF-β) signaling regulates cell-specific programs involved in embryonic development, wound-healing, and immune homeostasis. Yet, during tumor progression, these TGF-β-mediated programs are altered, leading to epithelial cell plasticity...
5.
Wright S, Vasilevski N, Serra V, Rodon J, Eichhorn P
Cancers (Basel)
. 2021 Apr;
13(7).
PMID: 33810522
The phosphatidylinositol-3-kinase (PI3K) pathway plays a central role in the regulation of several signalling cascades which regulate biological processes such as cellular growth, survival, proliferation, motility and angiogenesis. The hyperactivation...
6.
Jaynes P, Iyengar P, Lui S, Tan T, Vasilevski N, Wright S, et al.
Sci Rep
. 2020 Sep;
10(1):15725.
PMID: 32973272
Systematic control of the transforming growth factor-β (TGFβ) pathway is essential to keep the amplitude and the intensity of downstream signalling at appropriate levels. Ubiquitination plays a crucial role in...
7.
Lui S, Iyengar P, Jaynes P, Bin Adam Isa Z, Pang B, Tan T, et al.
EMBO Rep
. 2020 Jan;
21(1):e49618.
PMID: 31910334
No abstract available.
8.
Lui S, Iyengar P, Jaynes P, Bin Adam Isa Z, Pang B, Tan T, et al.
EMBO Rep
. 2019 Dec;
21(1):e47269.
PMID: 31858684
No abstract available.
9.
Sim W, Iyengar P, Lama D, Lui S, Ng H, Haviv-Shapira L, et al.
Nat Commun
. 2019 Nov;
10(1):5148.
PMID: 31704935
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
Sim W, Iyengar P, Lama D, Lui S, Ng H, Haviv-Shapira L, et al.
Nat Commun
. 2019 Sep;
10(1):4349.
PMID: 31554791
Treatment of muscle-invasive bladder cancer remains a major clinical challenge. Aberrant HGF/c-MET upregulation and activation is frequently observed in bladder cancer correlating with cancer progression and invasion. However, the mechanisms...