Pierre Mattar
Overview
Explore the profile of Pierre Mattar including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
827
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Recent Articles
1.
Clemot-Dupont S, Lourenco Fernandes J, Larrigan S, Sun X, Medisetti S, Stanley R, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(3):e2405981122.
PMID: 39808658
Although chromatin remodelers are among the most important risk genes associated with neurodevelopmental disorders (NDDs), the roles of these complexes during brain development are in many cases unclear. Here, we...
2.
Touahri Y, Hanna J, Tachibana N, Okawa S, Liu H, David L, et al.
Cell Rep
. 2024 Mar;
43(4):114005.
PMID: 38551961
The retina is exquisitely patterned, with neuronal somata positioned at regular intervals to completely sample the visual field. Here, we show that phosphatase and tensin homolog (Pten) controls starburst amacrine...
3.
Herrera I, Lourenco Fernandes J, Shir-Mohammadi K, Levesque J, Mattar P
Cell Death Dis
. 2023 Oct;
14(10):701.
PMID: 37880237
Neurodegenerative diseases are accompanied by dynamic changes in gene expression, including the upregulation of hallmark stress-responsive genes. While the transcriptional pathways that impart adaptive and maladaptive gene expression signatures have...
4.
Larrigan S, Joshi S, Mattar P
Hum Mol Genet
. 2023 Sep;
32(24):3361-3373.
PMID: 37738575
Chromatin remodellers are among the most important risk genes associated with neurodevelopmental disorders (NDDs), however, their functions during brain development are not fully understood. Here, we focused on Sifrim-Hitz-Weiss Syndrome...
5.
Boudreau-Pinsonneault C, David L, Lourenco Fernandes J, Javed A, Fries M, Mattar P, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(19):e2122168120.
PMID: 37126716
Temporal identity factors are sufficient to reprogram developmental competence of neural progenitors and shift cell fate output, but whether they can also reprogram the identity of terminally differentiated cells is...
6.
Kugler E, Bravo I, Durmishi X, Marcotti S, Beqiri S, Carrington A, et al.
Development
. 2023 Jan;
150(3).
PMID: 36625162
Cell morphology is crucial for all cell functions. This is particularly true for glial cells as they rely on complex shape to contact and support neurons. However, methods to quantify...
7.
Javed A, Santos-Franca P, Mattar P, Cui A, Kassem F, Cayouette M
Development
. 2022 Dec;
150(2).
PMID: 36537580
Temporal identity factors regulate competence of neural progenitors to generate specific cell types in a time-dependent manner, but how they operate remains poorly defined. In the developing mouse retina, the...
8.
Langouet M, Jolicoeur C, Javed A, Mattar P, Gearhart M, Daiger S, et al.
Sci Adv
. 2022 Sep;
8(36):eabh2868.
PMID: 36070393
Many transcription factors regulating the production, survival, and function of photoreceptor cells have been identified, but little is known about transcriptional co-regulators in retinal health and disease. Here, we show...
9.
Larrigan S, Shah S, Fernandes A, Mattar P
Int J Mol Sci
. 2021 May;
22(9).
PMID: 33946340
During brain development, the genome must be repeatedly reconfigured in order to facilitate neuronal and glial differentiation. A host of chromatin remodeling complexes facilitates this process. At the genetic level,...
10.
Mattar P, Jolicoeur C, Dang T, Shah S, Clark B, Cayouette M
Sci Rep
. 2021 Feb;
11(1):3858.
PMID: 33594190
Neural progenitor cells undergo identity transitions during development to ensure the generation different types of neurons and glia in the correct sequence and proportions. A number of temporal identity factors...