Pierre Mattar
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Explore the profile of Pierre Mattar including associated specialties, affiliations and a list of published articles.
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30
Citations
827
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Recent Articles
11.
Javed A, Mattar P, Lu S, Kruczek K, Kloc M, Gonzalez-Cordero A, et al.
Development
. 2020 Sep;
147(18).
PMID: 32878923
Multipotent retinal progenitor cells (RPCs) generate various cell types in a precise chronological order, but how exactly cone photoreceptor production is restricted to early stages remains unclear. Here, we show...
12.
Mattar P, Stevanovic M, Nad I, Cayouette M
Proc Natl Acad Sci U S A
. 2018 Aug;
115(34):E7987-E7996.
PMID: 30072429
Genome organization plays a fundamental role in the gene-expression programs of numerous cell types, but determinants of higher-order genome organization are poorly understood. In the developing mouse retina, rod photoreceptors...
13.
Tufford A, Onyak J, Sondereker K, Lucas J, Earley A, Mattar P, et al.
Cell Rep
. 2018 May;
23(8):2416-2428.
PMID: 29791852
Newborn neurons follow molecular cues to reach their final destination, but whether early life experience influences lamination remains largely unexplored. As light is among the first stimuli to reach the...
14.
Adnani L, Han S, Li S, Mattar P, Schuurmans C
Int Rev Cell Mol Biol
. 2018 Feb;
336:223-320.
PMID: 29413892
During fetal and postnatal development, the human brain generates 160 billion neuronal and glial cells, each with precise cellular phenotypes. To effectively manage such a complicated task, intrinsic (e.g., transcription...
15.
Mattar P, Cayouette M
Neurogenesis (Austin)
. 2016 Sep;
2(1):e1125409.
PMID: 27606333
While much progress has been made in recent years toward elucidating the transcription factor codes controlling how neural progenitor cells generate the various glial and neuronal cell types in a...
16.
Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1
DeGeer J, Kaplan A, Mattar P, Morabito M, Stochaj U, Kennedy T, et al.
J Cell Biol
. 2015 Sep;
210(5):817-32.
PMID: 26323693
During development, netrin-1 is both an attractive and repulsive axon guidance cue and mediates its attractive function through the receptor Deleted in Colorectal Cancer (DCC). The activation of Rho guanosine...
17.
Mattar P, Ericson J, Blackshaw S, Cayouette M
Neuron
. 2015 Feb;
85(3):497-504.
PMID: 25654255
Neural progenitors alter their output over time to generate different types of neurons and glia in specific chronological sequences, but this process remains poorly understood in vertebrates. Here we show...
18.
Touahri Y, Adnani L, Mattar P, Markham K, Klenin N, Schuurmans C
Curr Protoc Neurosci
. 2015 Jan;
70:1.22.1-1.22.25.
PMID: 25559002
This unit describes methods for non-isotopic RNA in situ hybridization on embryonic mouse sections. These methods can be used to follow the spatiotemporal dynamics of gene expression in an embryonic...
19.
Mattar P, Cayouette M
Neuron
. 2014 Dec;
84(5):885-8.
PMID: 25475182
Little is known about how vertebrate neural progenitors in a given spatial domain change their identity over time. In this issue of Neuron, Dias et al. (2014) discover that hindbrain...
20.
Li S, Mattar P, Dixit R, Lawn S, Wilkinson G, Kinch C, et al.
J Neurosci
. 2014 Feb;
34(6):2169-90.
PMID: 24501358
Neural cell fate specification is well understood in the embryonic cerebral cortex, where the proneural genes Neurog2 and Ascl1 are key cell fate determinants. What is less well understood is...