Francois Guillemot
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Explore the profile of Francois Guillemot including associated specialties, affiliations and a list of published articles.
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176
Citations
10386
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Recent Articles
1.
Peron A, DArco F, Aldinger K, Smith-Hicks C, Zweier C, Gradek G, et al.
Eur J Hum Genet
. 2024 Oct;
33(3):312-324.
PMID: 39448799
An increasing number of individuals with intellectual developmental disorder (IDD) and heterozygous variants in BCL11A are identified, yet our knowledge of manifestations and mutational spectrum is lacking. To address this,...
2.
Saenz-Antonanzas A, Munoz-Culla M, Rigo P, Ruiz-Barreiro L, Moreno-Valladares M, Alberro A, et al.
Aging Cell
. 2024 May;
23(8):e14201.
PMID: 38769809
The hippocampus is a brain area linked to cognition. The mechanisms that maintain cognitive activity in humans are poorly understood. Centenarians display extreme longevity which is generally accompanied by better...
3.
Bumetanide induces post-traumatic microglia-interneuron contact to promote neurogenesis and recovery
Tessier M, Garcia M, Goubert E, Blasco E, Consumi A, Dehapiot B, et al.
Brain
. 2023 Apr;
146(10):4247-4261.
PMID: 37082944
Although the Na-K-Cl cotransporter (NKCC1) inhibitor bumetanide has prominent positive effects on the pathophysiology of many neurological disorders, the mechanism of action is obscure. Attention paid to elucidating the role...
4.
Paun O, Tan Y, Patel H, Strohbuecker S, Ghanate A, Cobolli-Gigli C, et al.
Genes Dev
. 2023 Mar;
37(5-6):218-242.
PMID: 36931659
Pioneer transcription factors are thought to play pivotal roles in developmental processes by binding nucleosomal DNA to activate gene expression, though mechanisms through which pioneer transcription factors remodel chromatin remain...
5.
Kerloch T, Lepko T, Shkura K, Guillemot F, Gillotin S
J Vis Exp
. 2022 Nov;
(188).
PMID: 36342175
Adult Hippocampal Neurogenesis (AHN), which consists of a lifelong maintenance of proliferative and quiescent neural stem cells (NSCs) within the sub-granular zone (SGZ) of the dentate gyrus (DG) and their...
6.
Frederico B, Martins I, Chapela D, Gasparrini F, Chakravarty P, Ackels T, et al.
Dev Cell
. 2022 Aug;
57(16):1957-1975.e9.
PMID: 35998585
Cells with latent stem ability can contribute to mammalian tissue regeneration after damage. Whether the central nervous system (CNS) harbors such cells remains controversial. Here, we report that DNGR-1 lineage...
7.
Lattke M, Guillemot F
WIREs Mech Dis
. 2022 May;
14(5):e1557.
PMID: 35546493
Astrocytes are a major type of glial cells that have essential functions in development and homeostasis of the central nervous system (CNS). Immature astrocytes in the developing CNS support neuronal...
8.
Kerloch T, Farrugia F, Bouit L, Maitre M, Terral G, Koehl M, et al.
Mol Psychiatry
. 2021 Sep;
26(12):7280-7295.
PMID: 34561615
Despite the central role of Rho GTPases in neuronal development, their functions in adult hippocampal neurogenesis remain poorly explored. Here, by using a retrovirus-based loss-of-function approach in vivo, we show...
9.
Austin S, Gabarro-Solanas R, Rigo P, Paun O, Harris L, Guillemot F, et al.
Development
. 2021 Sep;
148(20).
PMID: 34557919
Adult mouse hippocampal neural stem cells (NSCs) generate new neurons that integrate into existing hippocampal networks and modulate mood and memory. These NSCs are largely quiescent and are stimulated by...
10.
Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
Lattke M, Goldstone R, Ellis J, Boeing S, Jurado-Arjona J, Marichal N, et al.
Nat Commun
. 2021 Jul;
12(1):4335.
PMID: 34267208
Astrocytes have essential functions in brain homeostasis that are established late in differentiation, but the mechanisms underlying the functional maturation of astrocytes are not well understood. Here we identify extensive...