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Michel Cayouette

Explore the profile of Michel Cayouette including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Olguin A, Rochon P, Theriault C, Brown T, Yao H, Cayouette M, et al.
Curr Biol . 2025 Mar; PMID: 40081378
Retinal interneurons and projection neurons (retinal ganglion cells, RGCs) connect in specific combinations in a specialized neuropil called the inner plexiform layer (IPL). The IPL is divided into multiple sublaminae,...
2.
Blackshaw S, Cayouette M
Curr Opin Neurobiol . 2025 Feb; 91:102976. PMID: 40010202
Regulation of neural progenitor temporal identity is critical to control the chronological order of cell birth and generation of cell diversity in the developing central nervous system (CNS). Single-cell RNA...
3.
Srikanta S, Brown T, Malescot A, Cloutier M, Zhu L, Coutanson C, et al.
J Neurochem . 2025 Feb; 169(2):e70018. PMID: 39967311
Ubiquitin-specific peptidase 2 (USP2) is a deubiquitinase (DUB) with a diversity of functions in physiology. One of these functions is the regulation of circadian rhythms, which are physiological rhythms with...
4.
Housset M, Filion D, Cortes N, Vali H, Mandato C, Casanova C, et al.
Dev Cell . 2024 Nov; 60(3):447-458.e5. PMID: 39561777
The coordinated spatial arrangement of organelles within a tissue plane, known as planar cell polarity (PCP), is critical for organ development and function. Gradients of morphogens and their receptors typically...
5.
Liu X, Yam P, Schlienger S, Cai E, Zhang J, Chen W, et al.
Nat Commun . 2024 Apr; 15(1):3365. PMID: 38664376
Hedgehog (Hh) signaling relies on the primary cilium, a cell surface organelle that serves as a signaling hub for the cell. Using proximity labeling and quantitative proteomics, we identify Numb...
6.
Touahri Y, Hanna J, Tachibana N, Okawa S, Liu H, David L, et al.
Cell Rep . 2024 Mar; 43(4):114005. PMID: 38551961
The retina is exquisitely patterned, with neuronal somata positioned at regular intervals to completely sample the visual field. Here, we show that phosphatase and tensin homolog (Pten) controls starburst amacrine...
7.
Fries M, Brown T, Jolicoeur C, Boulan B, Boudreau-Pinsonneault C, Javed A, et al.
Cell Rep . 2023 Aug; 42(8):112985. PMID: 37590135
The balance of contralateral and ipsilateral retinogeniculate projections is critical for binocular vision, but the transcriptional programs regulating this process remain ill defined. Here we show that the Pou class...
8.
Boudreau-Pinsonneault C, David L, Lourenco Fernandes J, Javed A, Fries M, Mattar P, et al.
Proc Natl Acad Sci U S A . 2023 May; 120(19):e2122168120. PMID: 37126716
Temporal identity factors are sufficient to reprogram developmental competence of neural progenitors and shift cell fate output, but whether they can also reprogram the identity of terminally differentiated cells is...
9.
Javed A, Santos-Franca P, Mattar P, Cui A, Kassem F, Cayouette M
Development . 2022 Dec; 150(2). PMID: 36537580
Temporal identity factors regulate competence of neural progenitors to generate specific cell types in a time-dependent manner, but how they operate remains poorly defined. In the developing mouse retina, the...
10.
Lacomme M, Hales S, Brown T, Stevanovic K, Jolicoeur C, Cai J, et al.
Sci Adv . 2022 Oct; 8(42):eabm4295. PMID: 36260685
Accumulation of the microtubule-associated protein Tau is linked to neuronal cell death in tauopathies, but how intraneuronal Tau levels are regulated in health and disease remains unclear. Here, we show...