Pierre H Vachon
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Explore the profile of Pierre H Vachon including associated specialties, affiliations and a list of published articles.
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25
Citations
634
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Recent Articles
11.
Gagne D, Groulx J, Benoit Y, Basora N, Herring E, Vachon P, et al.
J Cell Physiol
. 2009 Nov;
222(2):387-400.
PMID: 19885839
Integrin-linked kinase (ILK) plays a role in integrin signaling-mediated extracellular matrix (ECM)-cell interactions and also acts as a scaffold protein in functional focal adhesion points. In the present study, we...
12.
Demers M, Thibodeau S, Noel D, Fujita N, Tsuruo T, Gauthier R, et al.
J Cell Biochem
. 2009 May;
107(4):639-54.
PMID: 19479902
Herein, we investigated the survival roles of Fak, Src, MEK/Erk, and PI3-K/Akt-1 in intestinal epithelial cancer cells (HCT116, HT29, and T84), in comparison to undifferentiated and differentiated intestinal epithelial cells...
13.
Francoeur C, Bouatrouss Y, Seltana A, Pinchuk I, Vachon P, Powell D, et al.
Gastroenterology
. 2008 Nov;
136(1):268-277.e3.
PMID: 18976656
Background & Aims: Inflammatory bowel diseases (IBDs) are characterized by remodeling of the intestinal mucosa, which is associated with excessive cytokine release. Previous studies have shown that the epithelium in...
14.
Bouchard V, Harnois C, Demers M, Thibodeau S, Laquerre V, Gauthier R, et al.
Apoptosis
. 2008 Mar;
13(4):531-42.
PMID: 18322799
The molecular determinants which dictate survival and apoptosis/anoikis in human intestinal crypt cells remain to be fully understood. To this effect, the roles of beta1 integrin/Fak/Src signaling to the PI3-K/Akt-1,...
15.
Bouchard V, Demers M, Thibodeau S, Laquerre V, Fujita N, Tsuruo T, et al.
J Cell Physiol
. 2007 Apr;
212(3):717-28.
PMID: 17443665
Human intestinal epithelial cell survival and anoikis are distinctively regulated according to the state of differentiation. In the present study, we analyzed the roles of focal adhesion kinase (Fak)/Src signaling...
16.
Tremblay E, Auclair J, Delvin E, Levy E, Menard D, Pshezhetsky A, et al.
J Cell Biochem
. 2006 Jun;
99(4):1175-86.
PMID: 16795037
cDNA microarray technology enables detailed analysis of gene expression throughout complex processes such as differentiation. The aim of this study was to analyze the gene expression profile of normal human...
17.
Vachon P
Med Sci (Paris)
. 2006 Apr;
22(4):423-9.
PMID: 16597413
The regulatory mechanisms of cell survival and apoptosis are very complex in nature, implicating numerous players and signaling pathways not only in the decision-making process of surviving (or dying), but...
18.
Ni H, Dydensborg A, Herring F, Basora N, Gagne D, Vachon P, et al.
Oncogene
. 2005 Jul;
24(45):6820-9.
PMID: 16007143
The integrin beta4 subunit has been shown to be involved in various aspects of cancer progression. The aim of the present work was to evaluate the expression of beta4 in...
19.
Escaffit F, Perreault N, Jean D, Francoeur C, Herring E, Rancourt C, et al.
Exp Cell Res
. 2004 Nov;
302(2):206-20.
PMID: 15561102
In epithelia, abnormal expression of E-cadherin is related to pathologies involving a loss of cell polarization and/or differentiation. However, recent observations suggest that E-cadherin could also be repressed under physiological...
20.
Dufour G, Demers M, Gagne D, Dydensborg A, Teller I, Bouchard V, et al.
J Biol Chem
. 2004 Aug;
279(42):44113-22.
PMID: 15299029
We have shown previously that human intestinal epithelial cell survival and anoikis are distinctively regulated according to the state of differentiation. Here we analyzed the roles of protein kinase B/Akt...