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Jean-Francois Beaulieu

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Articles 111
Citations 5281
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Recent Articles
1.
Vahkal B, Altosaar I, Ariana A, Jabbour J, Pantieras F, Daniel R, et al.
Pediatr Res . 2024 Nov; PMID: 39609615
Human milk contains extracellular vesicles (EVs) that carry bioactive molecules such as microRNA, to the newborn intestine. The downstream effects of EV cargo on signaling and immune modulation may shield...
2.
Vahkal B, Altosaar I, Tremblay E, Gagne D, Huttman N, Minic Z, et al.
J Extracell Biol . 2024 Jun; 3(1):e128. PMID: 38938674
Human milk extracellular vesicles (HM EVs) are proposed to protect against disease development in infants. This protection could in part be facilitated by the bioactive EV cargo of proteins and...
3.
Cloutier G, Beaulieu J
Biomol Biomed . 2024 Apr; 24(5):1117-1132. PMID: 38606907
The 67 kDa laminin receptor (67LR) was identified as the first laminin receptor shown to be involved in the carcinogenesis of various cancers, including colorectal cancer. While the exact composition...
4.
Shajari E, Gagne D, Malick M, Roy P, Noel J, Gagnon H, et al.
Biomedicines . 2024 Feb; 12(2). PMID: 38397935
Inflammatory bowel disease (IBD) flare-ups exhibit symptoms that are similar to other diseases and conditions, making diagnosis and treatment complicated. Currently, the gold standard for diagnosing and monitoring IBD is...
5.
Mancuso C, Tremblay E, Gnodi E, Jean S, Beaulieu J, Barisani D
Int J Mol Sci . 2023 Sep; 24(17). PMID: 37685847
Metallic nanoparticles (mNPs) are widely used as food additives and can interact with gliadin triggering an immune response, but evaluation of the effects on crypts, hypertrophic in celiac subjects, is...
6.
Auclair N, Sane A, Ahmarani L, Ould-Chikh N, Patey N, Beaulieu J, et al.
J Lipid Res . 2023 Aug; 64(9):100423. PMID: 37558128
Biallelic pathogenic variants of the Sar1b gene cause chylomicron retention disease (CRD) whose central phenotype is the inability to secrete chylomicrons. Patients with CRD experience numerous clinical symptoms such as...
7.
Cloutier G, Seltana A, Fallah S, Beaulieu J
Exp Cell Res . 2023 Jul; 430(2):113723. PMID: 37499931
Intestinal epithelial cell differentiation is a highly controlled and orderly process occurring in the crypt so that cells migrating out to cover the villi are already fully functional. Absorptive cell...
8.
Senicourt B, Cloutier G, Basora N, Fallah S, Laniel A, Lavoie C, et al.
Cells . 2023 Apr; 12(7). PMID: 37048132
Primary cilia are sensory antennae located at the cell surface which mediate a variety of extracellular signals involved in development, tissue homeostasis, stem cells and cancer. Primary cilia are found...
9.
Gagne D, Shajari E, Thibault M, Noel J, Boisvert F, Babakissa C, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36232903
Necrotizing enterocolitis (NEC) is a life-threatening condition for premature infants in neonatal intensive care units. Finding indicators that can predict NEC development before symptoms appear would provide more time to...
10.
Seltana A, Cloutier G, Nicolas V, Khalfaoui T, Teller I, Perreault N, et al.
Front Immunol . 2022 Jul; 13:916187. PMID: 35812445
Fibrinogen is a large molecule synthesized in the liver and released in the blood. Circulating levels of fibrinogen are upregulated after bleeding or clotting events and support wound healing. In...