Takashi Tsuruo
Overview
Explore the profile of Takashi Tsuruo including associated specialties, affiliations and a list of published articles.
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Articles
163
Citations
4687
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Recent Articles
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Haga N, Saito S, Tsukumo Y, Sakurai J, Furuno A, Tsuruo T, et al.
Cancer Sci
. 2010 Mar;
101(5):1125-32.
PMID: 20210797
Cancer cells consume large amounts of glucose because of their specific metabolic pathway. However, cancer cells exist in tumor tissue where glucose is insufficient. To survive, cancer cells likely have...
3.
Ohishi T, Hirota T, Tsuruo T, Seimiya H
Cancer Res
. 2010 Feb;
70(5):2041-52.
PMID: 20160025
Aurora-A, a conserved serine-threonine kinase, plays essential roles in mitosis. Aberrant upregulation of Aurora-A perturbs proper mitotic progression and results in a generation of multinucleated cells with centrosome amplification. The...
4.
Katayama R, Ishioka T, Takada S, Takada R, Fujita N, Tsuruo T, et al.
J Cell Sci
. 2009 Dec;
123(Pt 1):23-8.
PMID: 20016063
Cellular FLIP (cFLIP) inhibits the apoptosis signaling initiated by death receptor ligation. We previously reported that a long form of cFLIP (cFLIP-L) enhances Wnt signaling via inhibition of beta-catenin ubiquitylation....
5.
Togano T, Sasaki M, Watanabe M, Nakashima M, Tsuruo T, Umezawa K, et al.
Biochem Biophys Res Commun
. 2009 Sep;
390(1):60-4.
PMID: 19778522
The biological basis of the resistance of solid tumor cells to chemotherapy is not well understood. While addressing this problem, we found that gastric cancer cell line St-4/CPT, lung cancer...
6.
Matsumura S, Sato S, Yudasaka M, Tomida A, Tsuruo T, Iijima S, et al.
Mol Pharm
. 2009 Sep;
6(2):441-7.
PMID: 19718797
Assured dispersibility is a prerequisite for clinical application of nanomaterials. Carbon nanomaterials have hydrophobic surfaces and thus readily agglomerate under aqueous conditions. Various conjugates composed of a carbon surface-binding moiety...
7.
Kim M, Maeng H, Yu K, Lee K, Tsuruo T, Kim D, et al.
J Pharm Sci
. 2009 Aug;
99(3):1548-66.
PMID: 19691109
The objective of this study was to characterize the mechanism that controls the transport of donepezil into the brain. The apparent brain uptake clearance (CL(app,br)) was decreased as a function...
8.
Katayama R, Koike S, Sato S, Sugimoto Y, Tsuruo T, Fujita N
Cancer Sci
. 2009 Aug;
100(11):2060-8.
PMID: 19673889
The ATP-binding cassette (ABC) transporters (ABC-T) actively efflux structurally and mechanistically unrelated anticancer drugs from cells. As a consequence, they can confer multidrug resistance (MDR) to cancer cells. ABC-T are...
9.
Tsukumo Y, Tsukahara S, Saito S, Tsuruo T, Tomida A
J Biol Chem
. 2009 Aug;
284(40):27500-10.
PMID: 19656946
NUCB1 (nucleobindin 1) is a Golgi-localized soluble protein with a signal peptide and multiple functional domains. We reported recently that NUCB1 is a negative regulator of the unfolded protein response...
10.
Miyawaki J, Matsumura S, Yuge R, Murakami T, Sato S, Tomida A, et al.
ACS Nano
. 2009 Jun;
3(6):1399-406.
PMID: 19480401
Single-walled carbon nanohorns (SWNHs) are single-graphene tubules that have shown high potential for drug delivery systems. In drug delivery, it is essential to quantitatively determine biodistribution and ultrastructural localization. However,...