Piero Giansanti
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Explore the profile of Piero Giansanti including associated specialties, affiliations and a list of published articles.
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33
Citations
1139
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Recent Articles
1.
Subramanian V, Juhr D, Giansanti P, Grumbach I
bioRxiv
. 2025 Jan;
PMID: 39868171
Background: Radiation therapy (RT) treats primary and metastatic brain tumors, with about one million Americans surviving beyond six months post-treatment. However, up to 90% of survivors experience RT-induced cognitive impairment....
2.
Fuchsl F, Untch J, Kavaka V, Zuleger G, Braun S, Schwanzer A, et al.
Nat Commun
. 2024 Dec;
15(1):10520.
PMID: 39627205
Neoantigen-specific T cell receptors (neoTCRs) promise safe, personalized anti-tumor immunotherapy. However, detailed assessment of neoTCR-characteristics affecting therapeutic efficacy is mostly missing. Previously, we identified diverse neoTCRs restricted to different neoantigens...
3.
Sperk A, Gabriel A, Koch D, Augsburger A, Sanchez V, Brockelt D, et al.
Leukemia
. 2024 Jul;
38(9):2027-2031.
PMID: 39014197
No abstract available.
4.
Subramanian V, Juhr D, Johnson L, Yem J, Giansanti P, Grumbach I
Oxid Med Cell Longev
. 2024 Jul;
2024:4887877.
PMID: 38962180
Approximately 70% of all strokes occur in patients over 65 years old, and stroke increases the risk of developing dementia. The circle of Willis (CoW), the ring of arteries at...
5.
Brunner S, Horing M, Liebisch G, Schweizer S, Scheiber J, Giansanti P, et al.
Life Sci Alliance
. 2024 Jun;
7(8).
PMID: 38843936
Lipid composition is conserved within sub-cellular compartments to maintain cell function. Lipidomic analyses of liver, muscle, white and brown adipose tissue (BAT) mitochondria revealed substantial differences in their glycerophospholipid (GPL)...
6.
Ecker V, Brandmeier L, Stumpf M, Giansanti P, Moreira A, Pfeuffer L, et al.
Cell Rep
. 2023 Oct;
42(10):113017.
PMID: 37792532
Despite available targeted treatments for the disease, drug-resistant chronic lymphocytic leukemia (CLL) poses a clinical challenge. The objective of this study is to examine whether the dual-specific phosphatases DUSP1 and...
7.
Giansanti P, Samaras P, Bian Y, Meng C, Coluccio A, Frejno M, et al.
Nat Methods
. 2022 Jun;
19(7):803-811.
PMID: 35710609
The laboratory mouse ranks among the most important experimental systems for biomedical research and molecular reference maps of such models are essential informational tools. Here, we present a quantitative draft...
8.
Oeckl J, Janovska P, Adamcova K, Bardova K, Brunner S, Dieckmann S, et al.
Mol Metab
. 2022 Apr;
61:101499.
PMID: 35470094
Objective: Classical ATP-independent non-shivering thermogenesis enabled by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) is activated, but not essential for survival, in the cold. It has long been...
9.
Systems approach reveals distinct and shared signaling networks of the four PGE receptors in T cells
Lone A, Giansanti P, Jorgensen M, Gjerga E, Dugourd A, Scholten A, et al.
Sci Signal
. 2021 Oct;
14(703):eabc8579.
PMID: 34609894
Prostaglandin E (PGE) promotes an immunosuppressive microenvironment in cancer, partly by signaling through four receptors (EP, EP, EP, and EP) on T cells. Here, we comprehensively characterized PGE signaling networks...
10.
Zhang X, Schuhmachers P, Mourao A, Giansanti P, Murer A, Thumann S, et al.
EMBO Rep
. 2021 Oct;
22(12):e53007.
PMID: 34605140
While Epstein-Barr virus (EBV) establishes a life-long latent infection in apparently healthy human immunocompetent hosts, immunodeficient individuals are at particular risk to develop lymphoproliferative B-cell malignancies caused by EBV. A...