Mathias Wilhelm
Overview
Explore the profile of Mathias Wilhelm including associated specialties, affiliations and a list of published articles.
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Articles
83
Citations
3968
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Recent Articles
1.
Xiao Z, Tushaus J, Kuster B, The M, Wilhelm M
J Proteome Res
. 2025 Mar;
PMID: 40052690
Mass spectrometry (MS)-based proteomics relies heavily on MS/MS (MS2) data, which do not fully exploit the available MS1 information. Traditional peptide identity propagation (PIP) methods, such as match-between-runs (MBR), are...
2.
Zhang N, Tang L, Li S, Liu L, Gao M, Wang S, et al.
Nat Commun
. 2025 Mar;
16(1):2200.
PMID: 40038279
Integration of multi-omics data can provide information on biomolecules from different layers to illustrate the complex biology systematically. Here, we build a multi-omics atlas containing 132,570 transcripts, 44,473 proteins, 19,970...
3.
Gabriel W, Gonzalez R, Laposchan S, Riedel E, Dundar G, Poppenberger B, et al.
Mol Cell Proteomics
. 2025 Feb;
24(3):100924.
PMID: 39921205
Citrullination is a critical yet understudied post-translational modification (PTM) implicated in various biological processes. Exploring its role in health and disease requires a comprehensive understanding of the prevalence of this...
4.
Abele M, Soleymaniniya A, Bayer F, Lomp N, Doll E, Meng C, et al.
Mol Cell Proteomics
. 2025 Jan;
24(3):100917.
PMID: 39880082
Mass spectrometry-based proteomics has revolutionized bacterial identification and elucidated many molecular mechanisms underlying bacterial growth, community formation, and drug resistance. However, most research has been focused on a few model...
5.
Muller J, Bayer F, Wilhelm M, Schuh M, Kuster B, The M
Nat Commun
. 2025 Jan;
16(1):510.
PMID: 39779715
Post-translational modifications (PTMs) play pivotal roles in regulating cellular signaling, fine-tuning protein function, and orchestrating complex biological processes. Despite their importance, the lack of comprehensive tools for studying PTMs from...
6.
He F, Aebersold R, Baker M, Bian X, Bo X, Chan D, et al.
Nature
. 2024 Dec;
637(8046):E22.
PMID: 39715925
No abstract available.
7.
He F, Aebersold R, Baker M, Bian X, Bo X, Chan D, et al.
Nature
. 2024 Dec;
636(8042):322-331.
PMID: 39663494
The human body contains trillions of cells, classified into specific cell types, with diverse morphologies and functions. In addition, cells of the same type can assume different states within an...
8.
Elhamraoui Z, Borras E, Wilhelm M, Sabido E
Anal Chem
. 2024 Sep;
96(40):15829-15833.
PMID: 39322219
Mass-spectrometry-based proteomics has advanced with the integration of experimental and predicted spectral libraries, which have significantly improved peptide identification in complex search spaces. However, challenges persist in distinguishing some peptides...
9.
Abbas Q, Wilhelm M, Kuster B, Poppenberger B, Frishman D
BMC Genomics
. 2024 Sep;
25(1):881.
PMID: 39300357
No abstract available.
10.
Hoffmann M, Poschenrieder J, Incudini M, Baier S, Fritz A, Maier A, et al.
Nucleic Acids Res
. 2024 Aug;
52(17):10144-10160.
PMID: 39175109
Most heritable diseases are polygenic. To comprehend the underlying genetic architecture, it is crucial to discover the clinically relevant epistatic interactions (EIs) between genomic single nucleotide polymorphisms (SNPs) (1-3). Existing...