Phillip J Stansfeld
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Explore the profile of Phillip J Stansfeld including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
3828
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Recent Articles
1.
Ashraf K, Bunoro-Batista M, Ansell T, Punetha A, Rosario-Garrido S, Firlar E, et al.
bioRxiv
. 2025 Feb;
PMID: 39974898
In Gram-negative bacteria, the enzymatic modification of Lipid A with aminoarabinose (L-Ara4N) leads to resistance against polymyxin antibiotics and cationic antimicrobial peptides. ArnC, an integral membrane glycosyltransferase, attaches a formylated...
2.
Fairbairn J, Kerr R, Pierre-White N, Jacovides A, Baileeves B, Stansfeld P, et al.
RSC Med Chem
. 2025 Feb;
PMID: 39944775
translocase MraY is the target for bacteriolytic protein E from bacteriophage ϕX174, interacting at a site close to Phe-288 on helix 9, on the extracellular face of the protein. A...
3.
K Lysyganicz P, Barbosa A, Khondker S, Stewart N, Carman G, Stansfeld P, et al.
EMBO J
. 2025 Jan;
44(3):781-800.
PMID: 39753951
Biogenesis of membrane-bound organelles involves the synthesis, remodeling, and degradation of their constituent phospholipids. How these pathways regulate organelle size remains poorly understood. Here we demonstrate that a lipid-degradation pathway...
4.
Liu Y, Brown C, Erramilli S, Su Y, Tseng P, Wang Y, et al.
bioRxiv
. 2024 Sep;
PMID: 39345558
The emergence of drug-resistant strains exacerbates the global challenge of tuberculosis caused by Mycobacterium tuberculosis (Mtb). Central to the pathogenicity of Mtb is its complex cell envelope, which serves as...
5.
Liu Y, Brown C, Borges N, Nobre R, Erramilli S, Dufrisne M, et al.
bioRxiv
. 2024 Sep;
PMID: 39345506
Tuberculosis (TB), exceeded in mortality only by COVID-19 among global infectious diseases, is caused by Mycobacterium tuberculosis (Mtb). The pathogenicity of Mtb is largely attributed to its complex cell envelope,...
6.
K Lysyganicz P, Barbosa A, Khondker S, Stewart N, Carman G, Stansfeld P, et al.
bioRxiv
. 2024 Sep;
PMID: 39282465
The biogenesis of membrane-bound organelles involves the synthesis, remodelling and degradation of their constituent phospholipids. How these pathways regulate organelle size, remains still poorly understood. Here we demonstrate that a...
7.
Wotherspoon P, Johnston H, Hardy D, Holyfield R, Bui S, Ratkeviciute G, et al.
Nat Commun
. 2024 Jul;
15(1):6394.
PMID: 39080293
The Maintenance of Lipid Asymmetry (Mla) pathway is a multicomponent system found in all gram-negative bacteria that contributes to virulence, vesicle blebbing and preservation of the outer membrane barrier function....
8.
von Kugelgen A, Cassidy C, van Dorst S, Pagani L, Batters C, Ford Z, et al.
Nature
. 2024 May;
630(8015):230-236.
PMID: 38811725
Nitrosopumilus maritimus is an ammonia-oxidizing archaeon that is crucial to the global nitrogen cycle. A critical step for nitrogen oxidation is the entrapment of ammonium ions from a dilute marine...
9.
Whitley K, Grimshaw J, Roberts D, Karinou E, Stansfeld P, Holden S
Nat Microbiol
. 2024 May;
9(11):3077.
PMID: 38750178
No abstract available.
10.
Urner L, Fiorentino F, Shutin D, Sauer J, Agasid M, El-Baba T, et al.
J Am Chem Soc
. 2024 Apr;
PMID: 38604609
Lipopolysaccharide (LPS) is vital for maintaining the outer membrane barrier in Gram-negative bacteria. LPS is also frequently obtained in complex with the inner membrane proteins after detergent purification. The question...