Phillip J Stansfeld
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Explore the profile of Phillip J Stansfeld including associated specialties, affiliations and a list of published articles.
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133
Citations
3828
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Recent Articles
11.
Whitley K, Grimshaw J, Roberts D, Karinou E, Stansfeld P, Holden S
Nat Microbiol
. 2024 Mar;
9(4):1064-1074.
PMID: 38480901
Bacterial cell division requires septal peptidoglycan (sPG) synthesis by the divisome complex. Treadmilling of the essential tubulin homologue FtsZ has been implicated in septal constriction, though its precise role remains...
12.
Marmont L, Orta A, Baileeves B, Sychantha D, Fernandez-Galliano A, Li Y, et al.
Nat Microbiol
. 2024 Feb;
9(3):763-775.
PMID: 38336881
Many bacterial surface glycans such as the peptidoglycan (PG) cell wall are built from monomeric units linked to a polyprenyl lipid carrier. How this limiting carrier is distributed among competing...
13.
Bohning J, Graham M, Letham S, Davis L, Schulze U, Stansfeld P, et al.
Nat Commun
. 2023 Dec;
14(1):8429.
PMID: 38114502
Inoviruses are filamentous phages infecting numerous prokaryotic phyla. Inoviruses can self-assemble into mesoscale structures with liquid-crystalline order, termed tactoids, which protect bacterial cells in Pseudomonas aeruginosa biofilms from antibiotics. Here,...
14.
Ansell T, Song W, Coupland C, Carrique L, Corey R, Duncan A, et al.
Nat Commun
. 2023 Nov;
14(1):7774.
PMID: 38012131
Cryo-electron microscopy (cryo-EM) enables the determination of membrane protein structures in native-like environments. Characterising how membrane proteins interact with the surrounding membrane lipid environment is assisted by resolution of lipid-like...
15.
LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry
Yang Y, Chen H, Corey R, Morales V, Quentin Y, Froment C, et al.
Nat Commun
. 2023 Oct;
14(1):6368.
PMID: 37821449
Insertion of lipopolysaccharide (LPS) into the bacterial outer membrane (OM) is mediated by a druggable OM translocon consisting of a β-barrel membrane protein, LptD, and a lipoprotein, LptE. The β-barrel...
16.
Cassidy C, Qin Z, Frosio T, Gosink K, Yang Z, Sansom M, et al.
mBio
. 2023 Sep;
14(5):e0079323.
PMID: 37772839
Bacterial chemotaxis is a ubiquitous behavior that enables cell movement toward or away from specific chemicals. It serves as an important model for understanding cell sensory signal transduction and motility....
17.
Nygaard R, Graham C, Dufrisne M, Colburn J, Pepe J, Hydorn M, et al.
Nat Commun
. 2023 Aug;
14(1):5151.
PMID: 37620344
Peptidoglycan (PG) is an essential structural component of the bacterial cell wall that is synthetized during cell division and elongation. PG forms an extracellular polymer crucial for cellular viability, the...
18.
Marmont L, Orta A, Corey R, Sychantha D, Galliano A, Li Y, et al.
bioRxiv
. 2023 Aug;
PMID: 37577621
Many bacterial surface glycans such as the peptidoglycan (PG) cell wall, O-antigens, and capsules are built from monomeric units linked to a polyprenyl lipid carrier. How this limiting lipid carrier...
19.
Xu D, Jiang W, Wu L, Gaudet R, Park E, Su M, et al.
Nature
. 2023 Jul;
619(7971):819-827.
PMID: 37438530
Understanding protective immunity to COVID-19 facilitates preparedness for future pandemics and combats new SARS-CoV-2 variants emerging in the human population. Neutralizing antibodies have been widely studied; however, on the basis...
20.
Fuss M, Wieferig J, Corey R, Hellmich Y, Tascon I, Sousa J, et al.
Nat Commun
. 2023 Jun;
14(1):3683.
PMID: 37344476
Cyclic di-AMP is the only known essential second messenger in bacteria and archaea, regulating different proteins indispensable for numerous physiological processes. In particular, it controls various potassium and osmolyte transporters...