Philippe Deterre
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Explore the profile of Philippe Deterre including associated specialties, affiliations and a list of published articles.
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26
Citations
838
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Recent Articles
11.
Kumar A, Martin K, Turner E, Buneker C, Dorgham K, Deterre P, et al.
PLoS One
. 2013 Feb;
8(2):e57230.
PMID: 23437346
Monocyte/macrophages are implicated in initiation of angiogenesis, tissue/organ perfusion and atherosclerosis biology. We recently showed that chemokine receptor CX(3)CR1 is an essential regulator of monocyte/macrophage derived smooth muscle cell differentiation...
12.
Darbandi-Tehrani K, Hermand P, Carvalho S, Dorgham K, Couvineau A, Lacapere J, et al.
FASEB J
. 2010 Jul;
24(11):4585-98.
PMID: 20667981
The chemokine CX3CL1 is expressed as a membrane protein that forms a potent adhesive pair with its unique receptor CX3CR1. This receptor has 3 natural variants, V249-T280 (VT), I249-T280 (IT),...
13.
Barbaux S, Poirier O, Pincet F, Hermand P, Tiret L, Deterre P
J Leukoc Biol
. 2010 Jan;
87(4):727-34.
PMID: 20051472
Interactions between P-sel and the PSGL-1 mediate the earliest adhesive events during an inflammatory response. Human PSGL-1 displays a high degree of genetic polymorphism that has been diversely associated with...
14.
Dorgham K, Ghadiri A, Hermand P, Rodero M, Poupel L, Iga M, et al.
J Leukoc Biol
. 2009 Jul;
86(4):903-11.
PMID: 19571253
Chemokines are mainly involved in the recruitment of leukocytes into tissues, a key feature of inflammation. Through its unique receptor CX3CR1, the chemokine CX3CL1 participates in diverse inflammatory processes including...
15.
Chabre M, Deterre P, Antonny B
Trends Pharmacol Sci
. 2009 Mar;
30(4):182-7.
PMID: 19269046
When the binding of one ligand to its receptor is influenced by a second ligand acting on a different receptor, one might assume that the receptors dimerize, enabling allosteric interactions...
16.
Rodero M, Marie Y, Coudert M, Blondet E, Mokhtari K, Rousseau A, et al.
J Clin Oncol
. 2008 Nov;
26(36):5957-64.
PMID: 19001328
Purpose: Few reliable prognostic molecular markers have been characterized for glioblastoma multiforme (GBM), considered the deadliest of human cancers. We hypothesized that genetic polymorphisms in chemokines and their receptors, which...
17.
Hermand P, Pincet F, Carvalho S, Ansanay H, Trinquet E, Daoudi M, et al.
J Biol Chem
. 2008 Aug;
283(44):30225-34.
PMID: 18725411
In its native form, the chemokine CX3CL1 is a firmly adhesive molecule promoting leukocyte adhesion and migration and hence involved, along with its unique receptor CX3CR1, in various inflammatory processes....
18.
Combadiere C, Feumi C, Raoul W, Keller N, Rodero M, Pezard A, et al.
J Clin Invest
. 2007 Oct;
117(10):2920-8.
PMID: 17909628
The role of retinal microglial cells (MCs) in age-related macular degeneration (AMD) is unclear. Here we demonstrated that all retinal MCs express CX3C chemokine receptor 1 (CX3CR1) and that homozygosity...
19.
Combadiere B, Combadiere C, Deterre P
Med Sci (Paris)
. 2007 Feb;
23(2):173-9.
PMID: 17291427
The immune system relies on the motility on various cell types that roam the host through the blood, the peripheral tissues and the lymphoid organs, looking for pathogens. Along their...
20.
Capoulade-Metay C, Ayouba A, Kfutwah A, Lole K, Petres S, Dudoit Y, et al.
Immunogenetics
. 2006 Jun;
58(7):533-41.
PMID: 16791620
The N-terminal domain of the chemokine CCL5/regulated upon activation normal T cell expressed and secreted (RANTES) has been shown to be critical for its biological activity on leukocytes. Several N-terminus-modified...