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Philippe Deterre

Explore the profile of Philippe Deterre including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 838
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Recent Articles
1.
Ostuni M, Hermand P, Saindoy E, Guillou N, Guellec J, Coens A, et al.
Sci Rep . 2020 Jun; 10(1):9069. PMID: 32494000
During inflammatory response, blood leukocytes adhere to the endothelium. This process involves numerous adhesion molecules, including a transmembrane chemokine, CX3CL1, which behaves as a molecular cluster. How this cluster assembles...
2.
Baudesson de Chanville C, Chousterman B, Hamon P, Laviron M, Guillou N, Loyher P, et al.
Front Immunol . 2020 May; 11:675. PMID: 32425929
Sepsis is characterized by a systemic inflammation that can cause an immune dysfunction, for which the underlying mechanisms are unclear. We investigated the impact of cecal ligature and puncture (CLP)-mediated...
3.
Dantzler K, Ma S, Ngotho P, Stone W, Tao D, Rijpma S, et al.
Sci Transl Med . 2019 Jun; 11(495). PMID: 31167926
The recent decline in global malaria burden has stimulated efforts toward elimination. Understanding the biology of malaria transmission stages may provide opportunities to reduce or prevent onward transmission to mosquitoes....
4.
Hermand P, Ciceron L, Pionneau C, Vaquero C, Combadiere C, Deterre P
Sci Rep . 2016 Sep; 6:33786. PMID: 27653778
Malaria caused by Plasmodium falciparum is associated with cytoadherence of infected red blood cells (iRBC) to endothelial cells. Numerous host molecules have been involved in cytoadherence, including the adhesive chemokine...
5.
Auvynet C, Baudesson de Chanville C, Hermand P, Dorgham K, Piesse C, Pouchy C, et al.
FASEB J . 2016 Mar; 30(6):2370-81. PMID: 26979087
CC chemokine receptor type 2 (CCR2) is a key molecule in inflammatory diseases and is an obvious drug target for the treatment of inflammation. A number of nonpeptidic, competitive CCR2...
6.
Felouzis V, Hermand P, Trambly de Laissardiere G, Combadiere C, Deterre P
Cell Signal . 2015 Oct; 28(1):120-9. PMID: 26515128
Chemokine receptors are members of the G-protein-coupled receptor (GPCR) family coupled to members of the Gi class, whose primary function is to inhibit the cellular adenylate cyclase. We used a...
7.
Chousterman B, Boissonnas A, Poupel L, Baudesson de Chanville C, Adam J, Tabibzadeh N, et al.
J Am Soc Nephrol . 2015 Jul; 27(3):792-803. PMID: 26160897
Monocytes have a crucial role in both proinflammatory and anti-inflammatory phenomena occurring during sepsis. Monocyte recruitment and activation are orchestrated by the chemokine receptors CX3CR1 and CCR2 and their cognate...
8.
Ostuni M, Guellec J, Hermand P, Durand P, Combadiere C, Pincet F, et al.
Biol Open . 2014 Nov; 3(12):1173-82. PMID: 25395671
The multi-domain CX3CL1 transmembrane chemokine triggers leukocyte adherence without rolling and migration by presenting its chemokine domain (CD) to its receptor CX3CR1. Through the combination of functional adhesion assays with...
9.
Poupel L, Boissonnas A, Hermand P, Dorgham K, Guyon E, Auvynet C, et al.
Arterioscler Thromb Vasc Biol . 2013 Jul; 33(10):2297-305. PMID: 23887641
Objective: Alterations of the chemokine receptor CX3CR1 gene were associated with a reduced risk of myocardial infarction in human and limited atherosclerosis in mice. In this study, we addressed whether...
10.
Jacquelin S, Licata F, Dorgham K, Hermand P, Poupel L, Guyon E, et al.
Blood . 2013 Jun; 122(5):674-83. PMID: 23775714
The chemokine receptor CCR2 controls the release of Ly6C(high) monocytes from the bone marrow and their recruitment to sites of inflammation. A second chemokine receptor, CX3CR1, is differentially expressed on...