Philippe Bouillet
Overview
Explore the profile of Philippe Bouillet including associated specialties, affiliations and a list of published articles.
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Articles
98
Citations
7173
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Recent Articles
1.
Audiger C, Laabi Y, Nie J, Gibson L, Wilson-Annan J, Brook-Carter P, et al.
Cell Rep
. 2024 Apr;
43(5):114159.
PMID: 38676923
The traditional view of hematopoiesis is that myeloid cells derive from a common myeloid progenitor (CMP), whereas all lymphoid cell populations, including B, T, and natural killer (NK) cells and...
2.
Dalseno D, Anderton H, Kueh A, Herold M, Silke J, Strasser A, et al.
Cell Death Dis
. 2023 Mar;
14(3):214.
PMID: 36973252
The cytokine TNF has essential roles in immune defence against diverse pathogens and, when its expression is deregulated, it can drive severe inflammatory disease. The control of TNF levels is...
3.
Clayer E, Frank D, Anderton H, Zhang S, Kueh A, Heim V, et al.
Immunol Cell Biol
. 2022 Jan;
100(3):160-173.
PMID: 35048402
The role of RNA-binding proteins of the CCCH-containing family in regulating proinflammatory cytokine production and inflammation is increasingly recognized. We have identified ZC3H12C (Regnase-3) as a potential post-transcriptional regulator of...
4.
Jain R, Zhao K, Sheridan J, Heinlein M, Kupresanin F, Abeysekera W, et al.
Cell Death Differ
. 2021 Aug;
28(10):2946-2956.
PMID: 34381167
Thymic epithelial cells (TECs) form a unique microenvironment that orchestrates T cell differentiation and immunological tolerance. Despite the importance of TECs for adaptive immunity, there is an incomplete understanding of...
5.
Clayer E, Dalseno D, Kueh A, Lacey D, Tsai M, Arvell E, et al.
iScience
. 2020 Nov;
23(11):101726.
PMID: 33210082
Post-transcriptional regulation mechanisms control mRNA stability or translational efficiency via ribosomes, and recent evidence indicates that it is a major determinant of the accurate levels of cytokine mRNAs. Transcriptional regulation...
6.
Kong I, Rimes J, Light A, Todorovski I, Jones S, Morand E, et al.
Cell Rep
. 2020 Oct;
33(3):108290.
PMID: 33086063
JQ1 is a BET-bromodomain inhibitor that has immunomodulatory effects. However, the precise molecular mechanism that JQ1 targets to elicit changes in antibody production is not understood. Our results show that...
7.
Nguyen P, Dagley L, Preaudet A, Lam N, Giam M, Fung K, et al.
Cell Death Differ
. 2019 Jul;
27(2):742-757.
PMID: 31296963
Gastrointestinal epithelial cells provide a selective barrier that segregates the host immune system from luminal microorganisms, thereby contributing directly to the regulation of homeostasis. We have shown that from early...
8.
Policheni A, Horikawa K, Milla L, Kofler J, Bouillet P, Belz G, et al.
Immunol Cell Biol
. 2019 May;
97(8):740-752.
PMID: 31087793
FOXP3 regulatory T (Treg) cells are essential for immunological tolerance and immune homeostasis. Despite a great deal of interest in modulating their number and function for the treatment of autoimmune...
9.
Vince J, De Nardo D, Gao W, Vince A, Hall C, McArthur K, et al.
Cell Rep
. 2018 Nov;
25(9):2339-2353.e4.
PMID: 30485804
Intrinsic apoptosis resulting from BAX/BAK-mediated mitochondrial membrane damage is regarded as immunologically silent. We show here that in macrophages, BAX/BAK activation results in inhibitor of apoptosis (IAP) protein degradation to...
10.
Chin H, Li M, Tan I, Ninnis R, Reljic B, Scicluna K, et al.
Nat Commun
. 2018 Nov;
9(1):4976.
PMID: 30478310
Intrinsic apoptosis is critical to prevent tumor formation and is engaged by many anti-cancer agents to eliminate tumor cells. BAX and BAK, the two essential mediators of apoptosis, are thought...