Philip J R Goulder
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Explore the profile of Philip J R Goulder including associated specialties, affiliations and a list of published articles.
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111
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8033
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Recent Articles
1.
Herbert N, Goulder P
Curr Opin HIV AIDS
. 2023 Jul;
18(5):229-236.
PMID: 37421384
Purpose Of Review: To review recent insights into the factors affecting HIV disease progression in children living with HIV, contrasting outcomes: following early ART initiation with those in natural, antiretroviral...
2.
Dolton G, Rius C, Hasan M, Wall A, Szomolay B, Behiry E, et al.
Cell
. 2022 Aug;
185(16):2936-2951.e19.
PMID: 35931021
We studied the prevalent cytotoxic CD8 T cell response mounted against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike glycoprotein epitope (sequence YLQPRTFLL) via the most frequent human leukocyte antigen...
3.
Bengu N, Mchunu N, Mokhethi S, Fillis R, Cromhout G, van Lobenstein J, et al.
Medicine (Baltimore)
. 2022 Jul;
101(27):e29228.
PMID: 35801794
Point-of-care (PoC) testing facilitates early infant diagnosis (EID) and treatment initiation, which improves outcome. We present a field evaluation of a new PoC test (Cepheid Xpert® HIV-1 Qual XC RUO)...
4.
Liu C, Zhou D, Nutalai R, Duyvesteyn H, Tuekprakhon A, Ginn H, et al.
Cell Host Microbe
. 2021 Dec;
30(1):53-68.e12.
PMID: 34921776
Alpha-B.1.1.7, Beta-B.1.351, Gamma-P.1, and Delta-B.1.617.2 variants of SARS-CoV-2 express multiple mutations in the spike protein (S). These may alter the antigenic structure of S, causing escape from natural or vaccine-induced...
5.
Vieira V, Adland E, Malone D, Martin M, Groll A, Ansari M, et al.
PLoS Pathog
. 2021 Nov;
17(11):e1010090.
PMID: 34793581
Natural Killer (NK) cells contribute to HIV control in adults, but HLA-B-mediated T-cell activity has a more substantial impact on disease outcome. However, the HLA-B molecules influencing immune control in...
6.
Vieira V, Adland E, Grayson N, Csala A, Richards F, Dacon C, et al.
J Virol
. 2021 Nov;
96(2):e0153521.
PMID: 34757843
HIV-specific CD8 T cells play a central role in immune control of adult HIV, but their contribution in pediatric infection is less well characterized. Previously, we identified a group of...
7.
Muenchhoff M, Chung A, Roider J, Dugast A, Richardson S, Kloverpris H, et al.
mSphere
. 2020 Dec;
5(6).
PMID: 33361123
A prophylactic HIV vaccine would ideally induce protective immunity prior to sexual debut. Children develop broadly neutralizing antibody (bnAb) responses faster and at higher frequencies than adults, but little is...
8.
Silva-Arrieta S, Goulder P, Brander C
PLoS Pathog
. 2020 Jun;
16(6):e1008607.
PMID: 32497149
No abstract available.
9.
Roider J, Porterfield J, Ogongo P, Muenchhoff M, Adland E, Groll A, et al.
Front Immunol
. 2019 Jul;
10:1497.
PMID: 31333650
Children may be the optimal target for HIV vaccine development as they generate substantially more frequent and more potent broadly HIV neutralizing antibodies (bnAbs) than adults. Development of a biomarker...
10.
McNaughton A, Lourenco J, Hattingh L, Adland E, Daniels S, Van Zyl A, et al.
BMC Med
. 2019 Feb;
17(1):43.
PMID: 30786896
Background: Sustainable Development Goals set a challenge for the elimination of hepatitis B virus (HBV) infection as a public health concern by the year 2030. Deployment of a robust prophylactic...