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Photini Kiepiela

Explore the profile of Photini Kiepiela including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 4361
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Recent Articles
1.
Vieira V, Lim N, Singh A, Leitman E, DSouza R, Adland E, et al.
JCI Insight . 2023 Jan; 8(3). PMID: 36602861
HIV nonprogression despite persistent viremia is rare among adults who are naive to antiretroviral therapy (ART) but relatively common among ART-naive children. Previous studies indicate that ART-naive pediatric slow progressors...
2.
Spooner E, Reddy T, Mchunu N, Reddy S, Daniels B, Ngomane N, et al.
J Glob Health . 2022 Feb; 12:04004. PMID: 35136596
Background: South Africa, with the highest burden of HIV infection globally, has made huge strides in its HIV/ART programme, but AIDS deaths have not decreased proportionally to ART uptake. Advanced...
3.
Millar J, Bengu N, Fillis R, Sprenger K, Ntlantsana V, Vieira V, et al.
EClinicalMedicine . 2020 Jun; 22:100344. PMID: 32510047
Background: Early combination antiretroviral therapy (cART) reduces the size of the viral reservoir in paediatric and adult HIV infection. Very early-treated children may have higher cure/remission potential. Methods: In an...
4.
Reddy S, Gibbs A, Spooner E, Ngomane N, Reddy T, Luthuli N, et al.
Diagnostics (Basel) . 2020 Feb; 10(2). PMID: 32024166
Background: The high burden of disease in South Africa presents challenges to public health services. Point-of-care (POC) technologies have the potential to address these gaps and improve healthcare systems. This...
5.
Daniels B, Coutsoudis A, Moodley-Govender E, Mulol H, Spooner E, Kiepiela P, et al.
Lancet Glob Health . 2019 Nov; 7(12):e1717-e1727. PMID: 31708152
Background: WHO guidelines recommend co-trimoxazole prophylaxis for HIV-exposed, HIV-uninfected infants. These guidelines date back to an era in which HIV testing of infants was impossible and mothers had poor access...
6.
Cloete C, Hampton J, Chetty T, Ngomane T, Spooner E, Zako L, et al.
South Afr J HIV Med . 2019 Oct; 20(1):985. PMID: 31616575
Background: With the largest antiretroviral therapy (ART) programme globally, demand for effective HIV management is increasing in South Africa. While viral load (VL) testing is conducted, VL follow-up and management...
7.
Chimukangara B, Lessells R, Rhee S, Giandhari J, Kharsany A, Naidoo K, et al.
EClinicalMedicine . 2019 May; 9:26-34. PMID: 31143879
Background: South Africa has the largest public antiretroviral therapy (ART) programme in the world. We assessed temporal trends in pretreatment HIV-1 drug resistance (PDR) in ART-naïve adults from South Africa....
8.
Skhosana M, Reddy S, Reddy T, Ntoyanto S, Spooner E, Ramjee G, et al.
South Afr J HIV Med . 2018 Mar; 17(1):444. PMID: 29568605
Introduction: Limited information is available on the usefulness of the PIMA™ analyser in predicting antiretroviral treatment eligibility and outcome in a primary healthcare clinic setting in disadvantaged communities in KwaZulu-Natal,...
9.
Leitman E, Thobakgale C, Adland E, Ansari M, Raghwani J, Prendergast A, et al.
J Exp Med . 2017 Oct; 214(11):3239-3261. PMID: 28983013
Recent studies have suggested greater HIV cure potential among infected children than adults. A major obstacle to HIV eradication in adults is that the viral reservoir is largely comprised of...
10.
Coutsoudis A, Daniels B, Moodley-Govender E, Ngomane N, Zako L, Spooner E, et al.
BMJ Open . 2016 Jul; 6(7):e010656. PMID: 27406638
Introduction: No randomised controlled trial (RCT) has examined the efficacy of cotrimoxazole (CTX) prophylaxis in HIV-exposed uninfected (HEU) infants during the breastfeeding period, in this new era of effective prevention...