Petter Storm
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Explore the profile of Petter Storm including associated specialties, affiliations and a list of published articles.
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2057
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Recent Articles
1.
Ambite I, Chao S, Rosenblad T, Hopkins R, Storm P, Ng Y, et al.
Life Sci Alliance
. 2025 Mar;
8(3).
PMID: 40036168
This study investigated the molecular basis of disease severity in acute pyelonephritis (APN), a common and potentially life-threatening bacterial infection. Two cohorts of infants with febrile urinary tract infection were...
2.
Fiorenzano A, Storm P, Sozzi E, Bruzelius A, Corsi S, Kajtez J, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(47):e2410331121.
PMID: 39541349
Dopaminergic (DA) neurons exhibit significant diversity characterized by differences in morphology, anatomical location, axonal projection pattern, and selective vulnerability to disease. More recently, scRNAseq has been used to map DA...
3.
Storm P, Zhang Y, Nilsson F, Fiorenzano A, Krausse N, Akerblom M, et al.
Sci Adv
. 2024 Oct;
10(42):eadn3057.
PMID: 39423273
Stem cell therapies for Parkinson's disease are at an exciting time of development, and several clinical trials have recently been initiated. Human pluripotent stem cells are differentiated into transplantable dopamine...
4.
Giacomoni J, Bruzelius A, Habekost M, Kajtez J, Ottosson D, Fiorenzano A, et al.
Cell Rep Methods
. 2024 Sep;
4(9):100845.
PMID: 39236715
Two-dimensional neuronal cultures have a limited ability to recapitulate the in vivo environment of the brain. Here, we introduce a three-dimensional in vitro model for human glia-to-neuron conversion, surpassing the...
5.
Kirkeby A, Nelander J, Hoban D, Rogelius N, Bjartmarz H, Storm P, et al.
Cell Stem Cell
. 2023 Oct;
30(10):1299-1314.e9.
PMID: 37802036
Cell replacement therapies for Parkinson's disease (PD) based on transplantation of pluripotent stem cell-derived dopaminergic neurons are now entering clinical trials. Here, we present quality, safety, and efficacy data supporting...
6.
Rajova J, Davidsson M, Avallone M, Hartnor M, Aldrin-Kirk P, Cardoso T, et al.
Mol Ther Methods Clin Dev
. 2023 May;
29:381-394.
PMID: 37251982
Cell therapy for Parkinson's disease has experienced substantial growth in the past decades with several ongoing clinical trials. Despite increasing refinement of differentiation protocols and standardization of the transplanted neural...
7.
Sozzi E, Kajtez J, Bruzelius A, Wesseler M, Nilsson F, Birtele M, et al.
Front Cell Dev Biol
. 2022 Oct;
10:1023279.
PMID: 36313550
Human pluripotent stem cells (hPSCs) are intrinsically able to self-organize into cerebral organoids that mimic features of developing human brain tissue. These three-dimensional structures provide a unique opportunity to generate...
8.
Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt J, Sozzi E, et al.
Development
. 2022 Oct;
149(23).
PMID: 36305490
Significant efforts are ongoing to develop refined differentiation protocols to generate midbrain dopamine (DA) neurons from pluripotent stem cells for application in disease modeling, diagnostics, drug screening and cell-based therapies...
9.
Drouin-Ouellet J, Legault E, Nilsson F, Pircs K, Bouquety J, Petit F, et al.
Stem Cell Reports
. 2022 Sep;
17(10):2203-2219.
PMID: 36150382
We have developed an efficient approach to generate functional induced dopaminergic (DA) neurons from adult human dermal fibroblasts. When performing DA neuronal conversion of patient fibroblasts with idiopathic Parkinson's disease...
10.
Asplund O, Storm P, Chandra V, Hatem G, Ottosson-Laakso E, Mansour-Aly D, et al.
Life Sci Alliance
. 2022 Aug;
5(12).
PMID: 35948367
Characterization of gene expression in pancreatic islets and its alteration in type 2 diabetes (T2D) are vital in understanding islet function and T2D pathogenesis. We leveraged RNA sequencing and genome-wide...