Catharina Svanborg
Overview
Explore the profile of Catharina Svanborg including associated specialties, affiliations and a list of published articles.
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110
Citations
2879
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Recent Articles
1.
Ambite I, Chao S, Rosenblad T, Hopkins R, Storm P, Ng Y, et al.
Life Sci Alliance
. 2025 Mar;
8(3).
PMID: 40036168
This study investigated the molecular basis of disease severity in acute pyelonephritis (APN), a common and potentially life-threatening bacterial infection. Two cohorts of infants with febrile urinary tract infection were...
2.
Ambite I, Wan M, Tran H, Nazari A, Chaudhuri A, Krintel C, et al.
Sci Rep
. 2025 Feb;
15(1):6778.
PMID: 40000737
Identifying specific inhibitors of the MYC oncogene has been challenging, due to off target effects associated with MYC inhibition. This study investigated how the recombinant Escherichia coli Lon protease (rLon),...
3.
Haq F, Sabari S, Hacek J, Brisuda A, Ambite I, Cavalera M, et al.
Cancer Med
. 2024 Sep;
13(17):e70149.
PMID: 39254154
Background: The tumoricidal complex alpha1-oleate targets bladder cancer cells, triggering rapid, apoptosis-like tumor cell death. Clinical effects of alpha1-oleate were recently observed in patients with non-muscle invasive bladder cancer (NMIBC),...
4.
Ahmadi S, Ambite I, Brisuda A, Hacek J, Haq F, Sabari S, et al.
Cancer Med
. 2024 Mar;
13(7):e7091.
PMID: 38553868
Background: The molecular content of urine is defined by filtration in the kidneys and by local release from tissues lining the urinary tract. Pathological processes and different therapies change the...
5.
Tran H, Wan M, Ambite I, Cavalera M, Grossi M, Hacek J, et al.
Sci Rep
. 2024 Feb;
14(1):3838.
PMID: 38360830
Though new targeted therapies for colorectal cancer, which progresses from local intestinal tumors to metastatic disease, are being developed, tumor specificity remains an important problem, and side effects a major...
6.
Ambite I, Tran T, Butler D, Cavalera M, Wan M, Ahmadi S, et al.
Pathogens
. 2024 Jan;
13(1).
PMID: 38251349
Innate immunity is essential for the anti-microbial defense, but excessive immune activation may cause severe disease. In this study, immunotherapy was shown to prevent excessive innate immune activation and restore...
7.
Hien T, Ambite I, Wan M, Cavalera M, Esmaeili P, Chaudhuri A, et al.
Int J Cancer
. 2023 Mar;
153(3):584-599.
PMID: 36891980
Bladder cancer is common and one of the most costly cancer forms, due to a lack of curative therapies. Recently, clinical safety and efficacy of the alpha1-oleate complex was demonstrated...
8.
Butler D, Ambite I, Wan M, Tran T, Wullt B, Svanborg C
Nat Rev Urol
. 2022 Jun;
19(7):419-437.
PMID: 35732832
Innovative solutions are needed for the treatment of bacterial infections, and a range of antibacterial molecules have been explored as alternatives to antibiotics. A different approach is to investigate the...
9.
Ho J, Mir S, Cavalera M, Esmaeili P, Tran T, Yann Z, et al.
Biofactors
. 2022 Apr;
48(5):1145-1159.
PMID: 35388547
Complexes formed by the alpha1 N-terminal peptide of alpha-lactalbumin and oleic acid (alpha1-oleate) interact with lipid bilayers. Plasma membrane perturbations trigger tumor cell death but normal differentiated cells are more...
10.
Ho J, Ambite I, Mok K, Babjuk M, Svanborg C
Mol Cell Oncol
. 2021 Dec;
8(5):1974278.
PMID: 34859140
The protein-lipid complex alpha1-oleate, derived from HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells), is identified as a molecular entity with significant therapeutic potential. Structural characterization of the complex and...