Peter Humphries
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Explore the profile of Peter Humphries including associated specialties, affiliations and a list of published articles.
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Articles
77
Citations
2425
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Recent Articles
31.
Campbell M, Humphries M, Humphries P
Methods Mol Biol
. 2012 Nov;
935:371-80.
PMID: 23150382
The inner blood-retina barrier (iBRB) is essential in restricting the movement of systemic components such as enzymes, anaphylatoxins, or pathogens that could otherwise enter the neural retina and cause extensive...
32.
Czekaj M, Haas J, Gebhardt M, Muller-Reichert T, Humphries P, Farrar J, et al.
PLoS One
. 2012 Aug;
7(7):e41798.
PMID: 22848612
Cell transplantation to treat retinal degenerative diseases represents an option for the replacement of lost photoreceptor cells. In vitro expandable cells isolated from the developing mammalian retina have been suggested...
33.
Hanrahan F, Humphries P, Campbell M
Ther Deliv
. 2012 Jul;
1(4):587-94.
PMID: 22833969
Efficient drug delivery to the brain or the eye remains a key challenge for future therapies directed against neurodegenerative disorders. Indeed it has been estimated that up to 98% of...
34.
Keaney J, Campbell M, Humphries P
Ther Deliv
. 2012 Jul;
2(11):1395-406.
PMID: 22826872
Over a decade has passed since the first description of RNAi in animals--the fundamental endogenous process by which small dsRNAs mediate sequence-specific gene silencing. This discovery has radically transformed our...
35.
Chadderton N, Palfi A, Millington-Ward S, Gobbo O, Overlack N, Carrigan M, et al.
Eur J Hum Genet
. 2012 Jun;
21(1):62-8.
PMID: 22669418
Leber hereditary optic neuropathy (LHON) is a mitochondrially inherited form of visual dysfunction caused by mutations in several genes encoding subunits of the mitochondrial respiratory NADH-ubiquinone oxidoreductase complex (complex I)....
36.
Campbell M, Hanrahan F, Gobbo O, Kelly M, Kiang A, Humphries M, et al.
Nat Commun
. 2012 May;
3:849.
PMID: 22617289
Traumatic brain injury is the leading cause of death in children and young adults globally. Malignant cerebral oedema has a major role in the pathophysiology that evolves after severe traumatic...
37.
Palfi A, Chadderton N, McKee A, Blanco Fernandez A, Humphries P, Kenna P, et al.
Hum Gene Ther
. 2012 May;
23(8):847-58.
PMID: 22545762
Recombinant adeno-associated virus (AAV) represents an efficient system for neuronal transduction. However, a potential drawback of AAV is its restricted packaging capacity of approximately 5 kb. To bypass this limitation,...
38.
Doyle S, Campbell M, Ozaki E, Salomon R, Mori A, Kenna P, et al.
Nat Med
. 2012 Apr;
18(5):791-8.
PMID: 22484808
Age-related macular degeneration (AMD) is the leading cause of central vision loss worldwide. Drusen accumulation is the major pathological hallmark common to both dry and wet AMD. Although activation of...
39.
Nguyen A, Campbell M, Kenna P, Kiang A, Tam L, Humphries M, et al.
Adv Exp Med Biol
. 2011 Dec;
723:547-52.
PMID: 22183376
No abstract available.
40.
Fischer M, Huber G, Paquet-Durand F, Humphries P, Redmond T, Grimm C, et al.
Adv Exp Med Biol
. 2011 Dec;
723:489-94.
PMID: 22183368
No abstract available.