Peter Chase
Overview
Explore the profile of Peter Chase including associated specialties, affiliations and a list of published articles.
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Articles
61
Citations
1548
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0
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Recent Articles
1.
Neuman H, Wilke L, Bozzuto L, Stelle L, Melnick D, Elezaby M, et al.
Clin Breast Cancer
. 2024 Nov;
25(1):56-64.
PMID: 39523128
Introduction: We sought to develop clinical guidelines within our multidisciplinary Breast Center to support decision-making for managing high-risk breast lesions. The objective is to describe the process used to develop...
2.
Liu Z, Chen K, Dai J, Xu P, Sun W, Liu W, et al.
Cell Res
. 2023 Jan;
33(1):55-70.
PMID: 36588115
Microphthalmia transcription factor (MITF) regulates melanocyte development and is the "lineage-specific survival" oncogene of melanoma. MITF is essential for melanoma initiation, progression, and relapse and has been considered an important...
3.
Chen J, Futran A, Crithary A, Li S, Wolicki A, Fogarty K, et al.
SLAS Discov
. 2020 Sep;
26(3):410-419.
PMID: 32935608
We previously developed a panel of one-step real-time quantitative reverse transcription PCR (one-step qRT-PCR; hereafter referred to as qRT-PCR) assays to assess compound efficacy. However, these high-cost, conventional qRT-PCR manual...
4.
Wang L, Cheng C, Qin J, Xu M, Kao C, Shi J, et al.
Sci Adv
. 2020 Jun;
6(18):eaaz8031.
PMID: 32494682
The orphan nuclear receptor COUP-TFII is expressed at a low level in adult tissues, but its expression is increased and shown to promote progression of multiple diseases, including prostate cancer,...
5.
Shou W, Gerritz S, Harden D, Lawrence R, Chase P, Chin J, et al.
SLAS Discov
. 2020 May;
26(2):242-247.
PMID: 32400264
Hits from high-throughput screening (HTS) assays are typically evaluated using cheminformatics and/or empirical approaches before a decision for follow-up (activity confirmation and/or sample resynthesis) is made. However, the compound integrity...
6.
Spicer T, Gardiner D, Schoenen F, Roy S, Griffin P, Chase P, et al.
SLAS Discov
. 2018 Aug;
24(1):38-46.
PMID: 30142014
Malaria remains a major cause of morbidity and mortality worldwide with ~3.3 billion people at risk of contracting malaria and an estimated 450,000 deaths each year. While tools to reduce...
7.
Nieto A, Fernandez-Vega V, Spicer T, Sturchler E, Adhikari P, Kennedy N, et al.
Assay Drug Dev Technol
. 2018 Jul;
16(5):278-288.
PMID: 30019946
GPR119 drug discovery efforts in the pharmaceutical industry for the treatment of type 2 diabetes mellitus (T2DM) and obesity, were initiated based on its restricted distribution in pancreas and GI...
8.
Chen J, Ribeiro B, Li H, Myer L, Chase P, Surti N, et al.
SLAS Discov
. 2017 Sep;
23(2):122-131.
PMID: 28957636
Chemotaxis is the directional movement of cells in response to a chemical stimulus and is vital for many physiological processes, including immune responses, tumor metastasis, wound healing, and blood vessel...
9.
Wang J, Fang P, Chase P, Tshori S, Razin E, Spicer T, et al.
SLAS Discov
. 2016 Nov;
22(1):58-66.
PMID: 27827304
Microphthalmia transcription factor (MITF) is a master transcription factor expressed in melanocytes, essential for melanocyte survival, differentiation, and pigment formation, and is a key oncogenic factor in melanoma initiation, migration,...
10.
Swingle M, Volmar C, Saldanha S, Chase P, Eberhart C, Salter E, et al.
SLAS Discov
. 2016 Sep;
22(1):21-31.
PMID: 27628691
Although there has been substantial success in the development of specific inhibitors for protein kinases, little progress has been made in the identification of specific inhibitors for their protein phosphatase...