Peter C Scacheri
Overview
Explore the profile of Peter C Scacheri including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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82
Citations
4930
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Recent Articles
11.
Gryder B, Scacheri P, Ried T, Khan J
Cold Spring Harb Perspect Biol
. 2021 Jun;
14(3).
PMID: 34187809
The change in cell state from normal to malignant is driven fundamentally by oncogenic mutations in cooperation with epigenetic alterations of chromatin. These alterations in chromatin can be a consequence...
12.
Huyghe J, Harrison T, Bien S, Hampel H, Figueiredo J, Schmit S, et al.
Gut
. 2021 Feb;
70(7):1325-1334.
PMID: 33632709
Objective: An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and repurposable...
13.
Lu L, Liu X, Huang W, Giusti-Rodriguez P, Cui J, Zhang S, et al.
Mol Cell
. 2020 Jun;
79(3):521-534.e15.
PMID: 32592681
Genome-wide mapping of chromatin interactions at high resolution remains experimentally and computationally challenging. Here we used a low-input "easy Hi-C" protocol to map the 3D genome architecture in human neurogenesis...
14.
Factor D, Barbeau A, Allan K, Hu L, Madhavan M, Hoang A, et al.
Cell
. 2020 Apr;
181(2):382-395.e21.
PMID: 32246942
Multiple sclerosis (MS) is an autoimmune disease characterized by attack on oligodendrocytes within the central nervous system (CNS). Despite widespread use of immunomodulatory therapies, patients may still face progressive disability...
15.
Morton A, Dogan-Artun N, Faber Z, MacLeod G, Bartels C, Piazza M, et al.
Cell
. 2019 Nov;
179(6):1330-1341.e13.
PMID: 31761532
Non-coding regions amplified beyond oncogene borders have largely been ignored. Using a computational approach, we find signatures of significant co-amplification of non-coding DNA beyond the boundaries of amplified oncogenes across...
16.
Bayles I, Krajewska M, Pontius W, Saiakhova A, Morrow J, Bartels C, et al.
J Clin Invest
. 2019 Sep;
129(10):4377-4392.
PMID: 31498151
Despite progress in intensification of therapy, outcomes for patients with metastatic osteosarcoma (OS) have not improved in thirty years. We developed a system that enabled preclinical screening of compounds against...
17.
Shang S, Yang J, Jazaeri A, Duval A, Tufan T, Lopes Fischer N, et al.
Cancer Res
. 2019 Jul;
79(18):4599-4611.
PMID: 31358529
Chemoresistance is driven by unique regulatory networks in the genome that are distinct from those necessary for cancer development. Here, we investigate the contribution of enhancer elements to cisplatin resistance...
18.
Bien S, Su Y, Conti D, Harrison T, Qu C, Guo X, et al.
Hum Genet
. 2019 Jun;
138(7):789-791.
PMID: 31254090
Every author has erroneously been assigned to the affiliation "62". The affiliation 62 belongs to the author Graham Casey.
19.
Mack S, Singh I, Wang X, Hirsch R, Wu Q, Villagomez R, et al.
J Exp Med
. 2019 Apr;
216(5):1071-1090.
PMID: 30948495
Glioblastoma is an incurable brain cancer characterized by high genetic and pathological heterogeneity. Here, we mapped active chromatin landscapes with gene expression, whole exomes, copy number profiles, and DNA methylomes...
20.
Bien S, Su Y, Conti D, Harrison T, Qu C, Guo X, et al.
Hum Genet
. 2019 Mar;
138(4):307-326.
PMID: 30820706
Genome-wide association studies have reported 56 independently associated colorectal cancer (CRC) risk variants, most of which are non-coding and believed to exert their effects by modulating gene expression. The computational...