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Peter B Farmer

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Articles 108
Citations 1744
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Recent Articles
1.
Jones D, Singh R, Emms V, Farmer P, Grant D, Quinn P, et al.
Rapid Commun Mass Spectrom . 2021 Dec; 36(6):e9245. PMID: 34939243
Rationale: Acrylamide is classified as a probable human carcinogen that is metabolised to glycidamide, which can covalently bind to DNA. The aim of this study was to investigate the formation...
2.
OCallaghan-Gordo C, Kogevinas M, Pedersen M, Fthenou E, Espinosa A, Tsiapa X, et al.
Eur J Nutr . 2016 Sep; 57(1):209-218. PMID: 27655526
Purpose: The study assessed whether diet and adherence to cancer prevention guidelines during pregnancy were associated with micronucleus (MN) frequency in mothers and newborns. MN is biomarkers of early genetic...
3.
Stone E, Citossi F, Singh R, Kaur B, Gaskell M, Farmer P, et al.
Bioorg Med Chem . 2015 Oct; 23(21):6891-9. PMID: 26474663
Potent, selective antitumour AhR ligands 5F 203 and GW 610 are bioactivated by CYPs 1A1 and 2W1. Herein we reason that DNA adducts' generation resulting in lethal DNA double strand...
4.
Westberg E, Singh R, Hedebrant U, Koukouves G, Souliotis V, Farmer P, et al.
Toxicol Lett . 2014 Sep; 232(1):28-36. PMID: 25261590
Stable and specific biomacromolecular adducts can be used to measure in vivo doses of reactive compounds. An LC/MS-MS method to measure adducts from the benzo[a]pyrene (BP) metabolite (±)-anti-BP-7,8-diol-9,10-epoxide ((±)-anti-BPDE) to...
5.
Pottenger L, Andrews L, Bachman A, Boogaard P, Cadet J, Embry M, et al.
Crit Rev Toxicol . 2014 Feb; 44(4):348-91. PMID: 24494825
The framework analysis previously presented for using DNA adduct information in the risk assessment of chemical carcinogens was applied in a series of case studies which place the adduct information...
6.
Merlo D, Agramunt S, Anna L, Besselink H, Botsivali M, Brady N, et al.
Environ Health Perspect . 2013 Nov; 122(2):193-200. PMID: 24252472
Background: Leukemia incidence has increased in recent decades among European children, suggesting that early-life environmental exposures play an important role in disease development. Objectives: We investigated the hypothesis that childhood...
7.
Pedersen M, Schoket B, Godschalk R, Wright J, von Stedingk H, Tornqvist M, et al.
Environ Health Perspect . 2013 Aug; 121(10):1200-6. PMID: 23906905
Background: Tobacco-smoke, airborne, and dietary exposures to polycyclic aromatic hydrocarbons (PAHs) have been associated with reduced prenatal growth. Evidence from biomarker-based studies of low-exposed populations is limited. Bulky DNA adducts...
8.
Lindberg H, Falck G, Singh R, Suhonen S, Jarventaus H, Vanhala E, et al.
Toxicology . 2012 Dec; 313(1):24-37. PMID: 23266321
Although some types of carbon nanotubes (CNTs) have been described to induce mesothelioma in rodents and genotoxic effects in various cell systems, there are few previous studies on the genotoxicity...
9.
Seow W, Pesatori A, Dimont E, Farmer P, Albetti B, Ettinger A, et al.
PLoS One . 2012 Dec; 7(12):e50471. PMID: 23227177
Chronic occupational exposure to benzene is associated with an increased risk of hematological malignancies such as acute myeloid leukemia (AML), but the underlying mechanisms are still unclear. The main objective...
10.
Barregard L, Moller P, Henriksen T, Mistry V, Koppen G, Rossner Jr P, et al.
Antioxid Redox Signal . 2012 Dec; 18(18):2377-91. PMID: 23198723
Aims: Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) is a widely used biomarker of oxidative stress. However, variability between chromatographic and ELISA methods hampers interpretation of data, and this variability may increase should urine...