Peter-Martin Bruch
Overview
Explore the profile of Peter-Martin Bruch including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
305
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0
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Recent Articles
1.
Lu Z, Stencel O, Liu W, Vasileiou E, Xu H, Pandey P, et al.
EMBO Mol Med
. 2025 Mar;
PMID: 40082582
Viral infections pose a significant global burden. Host susceptibility to pathogens is determined by many factors including genetic variation that can lead to immunodeficient or dysregulated antiviral immune responses. Pax5...
2.
Kobbe G, Bruggemann M, Baermann B, Wiegand L, Trautmann H, Yousefian S, et al.
N Engl J Med
. 2024 Nov;
391(13):1217-1226.
PMID: 39589371
The development of a fatal, clonal, autonomously proliferating CD4-CD8- chimeric antigen receptor (CAR)+ peripheral T-cell lymphoma (PTCL) occurred 1 month after a patient received treatment with tisagenlecleucel for relapsed primary...
3.
Schniederjohann C, Bruch P, Dietrich S, Neumann F
Methods Mol Biol
. 2024 Oct;
2865:375-393.
PMID: 39424733
High-plex imaging techniques enable the detection and quantification of a multitude of markers in tissue biopsies at single-cell or near-single-cell resolution. In lymphoma, this can facilitate the detection and characterization...
4.
Schmitt L, Hoppe J, Cea-Medina P, Bruch P, Krings K, Lechtenberg I, et al.
Cell Death Discov
. 2024 Jun;
10(1):279.
PMID: 38862521
A key feature of cancer is the disruption of cell cycle regulation, which is characterized by the selective and abnormal activation of cyclin-dependent kinases (CDKs). Consequently, targeting CDKs via meriolins...
5.
Brinkmann B, Floerchinger A, Schniederjohann C, Roider T, Coelho M, Mack N, et al.
Blood
. 2024 May;
144(7):784-789.
PMID: 38805637
Relapse after anti-CD19 chimeric antigen receptor (CD19-CAR) occurs in a substantial proportion of patients with lymphoid malignancies. We assessed the potential benefits of co-administering CD20-targeting bispecific antibodies (CD20-BsAbs) with CD19-CAR...
6.
Roessner P, Seufert I, Chapaprieta V, Jayabalan R, Briesch H, Massoni-Badosa R, et al.
Blood
. 2024 Apr;
144(5):510-524.
PMID: 38684038
The T-box transcription factor T-bet is known as a master regulator of the T-cell response but its role in malignant B cells has not been sufficiently explored. Here, we conducted...
7.
Rius Rigau A, Li Y, Matei A, Gyorfi A, Bruch P, Koziel S, et al.
Circ Res
. 2024 Mar;
134(7):875-891.
PMID: 38440901
Background: Systemic sclerosis (SSc) is a connective tissue disease that can serve as a model to study vascular changes in response to inflammation, autoimmunity, and fibrotic remodeling. Although microvascular changes...
8.
Roider T, Baertsch M, Fitzgerald D, Vohringer H, Brinkmann B, Czernilofsky F, et al.
Nat Cell Biol
. 2024 Feb;
26(3):478-489.
PMID: 38379051
The redirection of T cells has emerged as an attractive therapeutic principle in B cell non-Hodgkin lymphoma (B-NHL). However, a detailed characterization of lymphoma-infiltrating T cells across B-NHL entities is...
9.
Liebers N, Bruch P, Terzer T, Hernandez-Hernandez M, Paramasivam N, Fitzgerald D, et al.
Nat Cancer
. 2023 Oct;
4(12):1648-1659.
PMID: 37783805
Ex vivo drug response profiling is a powerful tool to study genotype-drug response associations and is being explored as a tool set for precision medicine in cancer. Here we conducted...
10.
Herbst S, Kim V, Roider T, Schitter E, Bruch P, Liebers N, et al.
Blood Adv
. 2023 Jun;
7(19):5925-5936.
PMID: 37352275
Large-scale compound screens are a powerful model system for understanding variability of treatment response and discovering druggable tumor vulnerabilities of hematological malignancies. However, as mostly performed in a monoculture of...