Perla Moreno-Castilla
Overview
Explore the profile of Perla Moreno-Castilla including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
248
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Recent Articles
1.
Velazquez-Delgado C, Hernandez-Ortiz E, Landa-Navarro L, Tapia-Rodriguez M, Moreno-Castilla P, Bermudez-Rattoni F
Psychopharmacology (Berl)
. 2024 Aug;
242(1):85-100.
PMID: 39145803
Rationale: The accumulation of beta-amyloid peptide (Aβ) in the forebrain leads to cognitive dysfunction and neurodegeneration in Alzheimer's disease. Studies have shown that individuals with a consistently cognitively active lifestyle...
2.
Costa K, Scholz R, Lloyd K, Moreno-Castilla P, Gardner M, Dayan P, et al.
Nat Neurosci
. 2022 Dec;
26(1):107-115.
PMID: 36550290
We use mental models of the world-cognitive maps-to guide behavior. The lateral orbitofrontal cortex (lOFC) is typically thought to support behavior by deploying these maps to simulate outcomes, but recent...
3.
Galvez-Marquez D, Salgado-Menez M, Moreno-Castilla P, Rodriguez-Duran L, Escobar M, Tecuapetla F, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(49):e2208254119.
PMID: 36442129
Detecting novelty is critical to consolidate declarative memories, such as spatial contextual recognition memory. It has been shown that stored memories, when retrieved, are susceptible to modification, incorporating new information...
4.
Myrum C, Moreno-Castilla P, Rapp P
Ageing Res Rev
. 2022 Jul;
80:101678.
PMID: 35781092
Arc is an effector immediate-early gene that is critical for forming long-term memories. Since its discovery 25 years ago, it has repeatedly surprised us with a number of intriguing properties,...
5.
Heras-Romero Y, Morales-Guadarrama A, Santana-Martinez R, Ponce I, Rincon-Heredia R, Poot-Hernandez A, et al.
Mol Ther
. 2021 Sep;
30(2):798-815.
PMID: 34563674
Spontaneous recovery after a stroke accounts for a significant part of the neurological recovery in patients. However limited, the spontaneous recovery is mechanistically driven by axonal restorative processes for which...
6.
Weiler M, Moreno-Castilla P, Starnes H, Melendez E, Stieger K, Long J, et al.
Brain Stimul
. 2021 Aug;
14(5):1219-1225.
PMID: 34400378
Background: Repetitive Transcranial Magnetic Stimulation (rTMS) has shown initial promise in combating age-related cognitive decline and dementia. The nature and severity of cognitive aging, however, varies markedly between individuals. Objective/hypothesis:...
7.
Yin W, Cerda-Hernandez N, Castillo-Morales A, Ruiz-Tejada-Segura M, Monzon-Sandoval J, Moreno-Castilla P, et al.
Front Neurosci
. 2021 Jan;
14:602642.
PMID: 33390887
Alzheimer's disease (AD)-related degenerative decline is associated to the presence of amyloid beta (Aβ) plaque lesions and neuro fibrillary tangles (NFT). However, the precise molecular mechanisms linking Aβ deposition and...
8.
De la Fuente-Munoz C, Rosas-Lemus M, Moreno-Castilla P, Bermudez-Rattoni F, Uribe-Carvajal S, Arias C
Int J Mol Sci
. 2020 Nov;
21(22).
PMID: 33227902
Synaptic aging has been associated with neuronal circuit dysfunction and cognitive decline. Reduced mitochondrial function may be an early event that compromises synaptic integrity and neurotransmission in vulnerable brain regions...
9.
Gil-Lievana E, Balderas I, Moreno-Castilla P, Luis-Islas J, McDevitt R, Tecuapetla F, et al.
Commun Biol
. 2020 Mar;
3(1):139.
PMID: 32198461
Findings have shown that anterior insular cortex (aIC) lesions disrupt the maintenance of drug addiction, while imaging studies suggest that connections between amygdala and aIC participate in drug-seeking. However, the...
10.
Moreno-Castilla P, Perez-Ortega R, Violante-Soria V, Balderas I, Bermudez-Rattoni F
Hippocampus
. 2017 Feb;
27(5):547-557.
PMID: 28176408
The detection and processing of novel information encountered in our environment is crucial for proper adaptive behavior and learning. Hippocampus is a prime structure for novelty detection that receives high-level...