Pengju Nie
Overview
Explore the profile of Pengju Nie including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
193
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0
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Recent Articles
1.
Nie P, Wu Y, Robinson J, Mekala S, Lee V, Li Y
ACS Chem Biol
. 2025 Mar;
PMID: 40079621
Tau aggregation plays a crucial role in the development of Alzheimer's disease (AD). Developing specific techniques that can isolate pathogenic tau from brain tissue is important for understanding tauopathies and...
2.
Chase D, Bebenek A, Nie P, Jaime-Figueroa S, Butrin A, Castro D, et al.
Angew Chem Int Ed Engl
. 2024 Feb;
63(14):e202316496.
PMID: 38348945
Brachyury is an oncogenic transcription factor whose overexpression drives chordoma growth. The downmodulation of brachyury in chordoma cells has demonstrated therapeutic potential, however, as a transcription factor it is classically...
3.
Dai J, Liu T, Torigian D, Tong Y, Han S, Nie P, et al.
Med Image Anal
. 2023 Oct;
91:102987.
PMID: 37837691
Purpose: Body composition analysis (BCA) of the body torso plays a vital role in the study of physical health and pathology and provides biomarkers that facilitate the diagnosis and treatment...
4.
Dai J, Udupa J, Torigian D, Tong Y, Nie P, Zhang J, et al.
Proc SPIE Int Soc Opt Eng
. 2023 Jun;
12468.
PMID: 37261083
Measurement of body composition, including multiple types of adipose tissue, skeletal tissue, and skeletal muscle, on computed tomography (CT) images is practical given the powerful anatomical structure visualization ability of...
5.
Nie P, Kalidindi T, Nagle V, Wu X, Li T, Liao G, et al.
Clin Cancer Res
. 2021 Sep;
27(22):6145-6155.
PMID: 34475100
Purpose: Abnormal Notch signaling promotes cancer cell growth and tumor progression in various cancers. Targeting γ-secretase, a pivotal regulator in the Notch pathway, has yielded numerous γ-secretase inhibitors (GSIs) for...
6.
Hur J, Frost G, Wu X, Crump C, Pan S, Wong E, et al.
Nature
. 2020 Sep;
586(7831):735-740.
PMID: 32879487
Innate immunity is associated with Alzheimer's disease, but the influence of immune activation on the production of amyloid-β is unknown. Here we identify interferon-induced transmembrane protein 3 (IFITM3) as a...
7.
Nie P, Vartak A, Li Y
Semin Cell Dev Biol
. 2020 Apr;
105:43-53.
PMID: 32249070
Over two decades, γ-secretase has been the target for extensive therapeutic development due to its pivotal role in pathogenesis of Alzheimer's disease and cancer. However, it has proven to be...
8.
Hu J, Xu H, Nie P, Xie X, Nie Z, Rao Y
Chemistry
. 2014 Mar;
20(14):3932-8.
PMID: 24590598
A transition-metal-free oxidative C-N coupling method has been developed for the synthesis of 1H-azaindazoles and 1H-indazoles from easily accessible hydrazones. The procedure uses TEMPO, a basic additive, and dioxygen gas...