Pedro Cutillas
Overview
Explore the profile of Pedro Cutillas including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
33
Citations
1028
Followers
0
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Recent Articles
1.
Dembitz V, Lawson H, Burt R, Natani S, Philippe C, James S, et al.
Leukemia
. 2024 Aug;
38(11):2395-2409.
PMID: 39187579
Identification of specific and therapeutically actionable vulnerabilities, ideally present across multiple mutational backgrounds, is needed to improve acute myeloid leukemia (AML) patients' outcomes. We identify stearoyl-CoA desaturase (SCD), the key...
2.
Cubuk C, Lau R, Cutillas P, Rajeeve V, John C, Surace A, et al.
Arthritis Res Ther
. 2024 Jun;
26(1):120.
PMID: 38867295
Background: Kinases are intracellular signalling mediators and key to sustaining the inflammatory process in rheumatoid arthritis (RA). Oral inhibitors of Janus Kinase family (JAKs) are widely used in RA, while...
3.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley C, et al.
Nat Cell Biol
. 2024 May;
26(6):1019.
PMID: 38778130
No abstract available.
4.
Koenis D, De Matteis R, Rajeeve V, Cutillas P, Dalli J
Adv Sci (Weinh)
. 2023 Dec;
11(7):e2304690.
PMID: 38064171
Clearance of multiple rounds of apoptotic cells (ACs) through continual efferocytosis is critical in the maintenance of organ function, the resolution of acute inflammation, and tissue repair. To date, little...
5.
Di Mambro A, Arroyo-Berdugo Y, Fioretti T, Randles M, Cozzuto L, Rajeeve V, et al.
Oncogene
. 2023 Oct;
42(50):3670-3683.
PMID: 37891368
KMT2A-rearranged (KMT2A-R) is an aggressive and chemo-refractory acute leukemia which mostly affects children. Transcriptomics-based characterization and chemical interrogation identified kinases as key drivers of survival and drug resistance in KMT2A-R...
6.
Prieto-Fernandez L, Villaronga M, Hermida-Prado F, Hijazi M, Montoro-Jimenez I, Pevida M, et al.
Biomed Pharmacother
. 2023 Mar;
158:114176.
PMID: 36916400
Background: Cancer-associated fibroblasts (CAFs) are major players in tumor-stroma communication, and participate in several cancer hallmarks to drive tumor progression and metastatic dissemination. This study investigates the driving effects of...
7.
Hayat A, Carter E, King H, Ors A, Doe A, Teijeiro S, et al.
Dis Model Mech
. 2023 Jan;
16(2).
PMID: 36661191
Overexpression of the HER2 protein in breast cancer patients is a predictor of poor prognosis and resistance to therapies. We used an inducible breast cancer transformation system that allows investigation...
8.
El-Mansi S, Robinson C, Kostelnik K, McCormack J, Mitchell T, Lobato-Marquez D, et al.
Blood
. 2022 Dec;
141(8):930-944.
PMID: 36564030
In response to tissue injury, within seconds the ultra-large glycoprotein von Willebrand factor (VWF) is released from endothelial storage organelles (Weibel-Palade bodies) into the lumen of the blood vasculature, where...
9.
Murray E, Menezes S, Henry J, Williams J, Alba-Castellon L, Baskaran P, et al.
Cell Rep
. 2022 Jan;
38(4):110227.
PMID: 35081338
In pancreatic ductal adenocarcinoma (PDAC), differentiation of pancreatic stellate cells (PSCs) into myofibroblast-like cancer-associated fibroblasts (CAFs) can both promote and suppress tumor progression. Here, we show that the Rho effector...
10.
Freire-Beneitez V, Pomella N, Millner T, Dumas A, Niklison-Chirou M, Maniati E, et al.
NAR Cancer
. 2021 Jul;
3(2):zcab020.
PMID: 34319293
[This corrects the article DOI: 10.1093/narcan/zcab009.].