Pawan Noel
Overview
Explore the profile of Pawan Noel including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
798
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Recent Articles
1.
Kostenko S, Khatua B, Trivedi S, Narayana Pillai A, McFayden B, Morsy M, et al.
Gastroenterology
. 2023 Jun;
165(4):999-1015.
PMID: 37263302
Background & Aims: Although transient bacteremia is common during dental and endoscopic procedures, infections developing during sterile diseases like acute pancreatitis (AP) can have grave consequences. We examined how impaired...
2.
Khatua B, El-Kurdi B, Patel K, Rood C, Noel P, Crowell M, et al.
Sci Adv
. 2021 Jan;
7(5).
PMID: 33514548
Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses. Since adipose triglyceride composition corresponds to long-term dietary patterns,...
3.
Noel P, Hussein S, Ng S, Antal C, Lin W, Rodela E, et al.
Oncogenesis
. 2020 Nov;
9(11):100.
PMID: 33168807
The tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) is highly heterogeneous, fibrotic, and hypovascular, marked by extensive desmoplasia and maintained by the tumor cells, cancer-associated fibroblasts (CAFs) and other stromal...
4.
Lin W, Noel P, Borazanci E, Lee J, Amini A, Han I, et al.
Genome Med
. 2020 Sep;
12(1):80.
PMID: 32988401
Background: Solid tumors such as pancreatic ductal adenocarcinoma (PDAC) comprise not just tumor cells but also a microenvironment with which the tumor cells constantly interact. Detailed characterization of the cellular...
5.
de Oliveira C, Khatua B, Noel P, Kostenko S, Bag A, Balakrishnan B, et al.
J Clin Invest
. 2020 Jan;
130(4):1931-1947.
PMID: 31917686
Visceral adipose tissue plays a critical role in numerous diseases. Although imaging studies often show adipose involvement in abdominal diseases, their outcomes may vary from being a mild self-limited illness...
6.
Wiedmeier J, Noel P, Lin W, Von Hoff D, Han H
Cancer Treat Res
. 2019 Jun;
178:237-252.
PMID: 31209848
The application of next-generation sequencing in cancer genomics allowed for a better understanding of the genetics and pathogenesis of cancer. Single-cell genomics is a relatively new field that has enhanced...
7.
Noel P, Von Hoff D, Saluja A, Velagapudi M, Borazanci E, Han H
Trends Pharmacol Sci
. 2019 Apr;
40(5):327-341.
PMID: 30975442
Triptolide, a compound isolated from a Chinese medicinal herb, possesses potent antitumor, immunosuppressive, and anti-inflammatory properties, but is clinically limited due to its poor solubility, bioavailability, and toxicity. Recently, Minnelide,...
8.
Lytle N, Ferguson L, Rajbhandari N, Gilroy K, Fox R, Deshpande A, et al.
Cell
. 2019 Apr;
177(3):572-586.e22.
PMID: 30955884
Drug resistance and relapse remain key challenges in pancreatic cancer. Here, we have used RNA sequencing (RNA-seq), chromatin immunoprecipitation (ChIP)-seq, and genome-wide CRISPR analysis to map the molecular dependencies of...
9.
Khatua B, Trivedi R, Noel P, Patel K, Singh R, de Oliveira C, et al.
Am J Pathol
. 2019 Apr;
189(6):1226-1240.
PMID: 30954473
Acute lipolysis of visceral fat or circulating triglycerides may worsen acute pancreatitis (AP)-associated local and systemic injury. The pancreas expresses pancreatic triacylglycerol lipase (PNLIP), pancreatic lipase-related protein 2 (PNLIPRP2), and...
10.
Xie P, Gao M, Wang C, Zhang J, Noel P, Yang C, et al.
Nucleic Acids Res
. 2019 Feb;
47(8):e48.
PMID: 30799483
Characterization of individual cell types is fundamental to the study of multicellular samples. Single-cell RNAseq techniques, which allow high-throughput expression profiling of individual cells, have significantly advanced our ability of...