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Pawan Malhotra

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Articles 114
Citations 1737
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Recent Articles
1.
Nema S, Rathore S, Mohmmed A, Malhotra P
Trans R Soc Trop Med Hyg . 2025 Feb; PMID: 39921411
Malaria vaccines are crucial for advancing public health and achieving malaria elimination. Currently, pre-erythrocytic vaccines like RTS, S/AS01 and R21/Matrix-M are in use, but their effectiveness is limited. Ongoing research...
2.
Nanda S, Pandey R, Sardar R, Panda A, Naorem A, Gupta D, et al.
Heliyon . 2024 Oct; 10(19):e38500. PMID: 39391471
, which causes life-threatening cerebral malaria has rapidly gained resistance against most frontline anti-malarial drugs, thereby generating an urgent need to develop novel therapeutic approaches. Conducting in-depth investigations on in...
3.
Djuidje Chatue I, Nyegue M, Kamdem S, Maloba F, Taliy Junaid I, Malhotra P, et al.
PLOS Glob Public Health . 2024 Aug; 4(8):e0003556. PMID: 39133703
Malaria kills nearly 619,000 people each year. Despite the natural immunity acquired to malaria, pregnant women and children under five die from severe forms of the disease in sub-Saharan Africa....
4.
Kaul S, Nair V, Gcanga L, Lakshmanan V, Kalamuddin M, Anang V, et al.
Int J Biol Macromol . 2024 May; 271(Pt 2):132714. PMID: 38815937
Objectives: The study aimed to identify a quantitative signature of circulating small non-coding RNAs (sncRNAs) as a biomarker for pulmonary tuberculosis disease (active-TB/ATB) and explore their regulatory roles in host-pathogen...
5.
Agrawal P, Kumari S, Mohmmed A, Malhotra P, Sharma U, Sahal D
ACS Omega . 2023 Oct; 8(41):38506-38523. PMID: 37867646
Phylum apicomplexan consists of parasites, such as and . These obligate intracellular parasites enter host cells an energy-dependent process using specialized machinery, called the glideosome. In the present study, we...
6.
Jameel E, Madhav H, Agrawal P, Raza M, Ahmedi S, Rahman A, et al.
J Biomol Struct Dyn . 2023 Mar; 41(24):15485-15506. PMID: 36970842
Malaria still threatens half the globe population despite successful Artemisinin-based combination therapy. One of the reasons for our inability to eradicate malaria is the emergence of resistance to current antimalarials....
7.
Arora P, Narwal M, Thakur V, Mukhtar O, Malhotra P, Mohmmed A
Biochem J . 2022 Dec; 480(1):25-39. PMID: 36511651
Proteins associated with ubiquitin-proteasome system (UPS) are potential drug targets in the malaria parasite. The ubiquitination and deubiquitination are key regulatory processes for the functioning of UPS. In this study,...
8.
Gupta P, Pandey R, Thakur V, Parveen S, Kaur I, Panda A, et al.
FASEB Bioadv . 2022 Oct; 4(10):662-674. PMID: 36238365
Hemoglobin degradation is crucial for the growth and survival of in human erythrocytes. Although the process of Hb degradation has been studied in detail, the mechanisms of Hb uptake remain...
9.
Singh A, Kalamuddin M, Mohmmed A, Malhotra P, Hoda N
RSC Adv . 2022 May; 9(67):39410-39421. PMID: 35540629
Falcipain-2 (FP2) is a papain family cysteine protease and a key member of the hemoglobin degradation pathway, a process that is required at erythrocytic stages of to obtain amino acids....
10.
Kaul S, Nair V, Birla S, Dhawan S, Rathore S, Khanna V, et al.
Microbiol Spectr . 2022 Apr; 10(2):e0244521. PMID: 35416716
Diagnosis of latent tuberculosis infection (LTBI) using biomarkers in order to identify the risk of progressing to active TB and therefore predicting a preventive therapy has been the main bottleneck...