Pavel Sova
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Explore the profile of Pavel Sova including associated specialties, affiliations and a list of published articles.
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22
Citations
1162
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Recent Articles
1.
Ulyanova T, Cherone J, Sova P, Papayannopoulou T
Exp Hematol
. 2022 Mar;
108:16-25.
PMID: 35227527
The functional impact of integrin expression in erythropoiesis has been previously emphasized through its decisive influence on erythroid cell-microenvironment (matrix and cellular) interactions, especially under conditions of stress. Beyond that,...
2.
Li C, Psatha N, Sova P, Gil S, Wang H, Kim J, et al.
Blood
. 2018 May;
131(26):2915-2928.
PMID: 29789357
Disorders involving β-globin gene mutations, primarily β-thalassemia and sickle cell disease, represent a major target for hematopoietic stem/progenitor cell (HSPC) gene therapy. This includes CRISPR/Cas9-mediated genome editing approaches in adult...
3.
Vragniau C, Hubner J, Beidler P, Gil S, Saydaminova K, Lu Z, et al.
J Virol
. 2017 Jan;
91(6).
PMID: 28077642
Defensins are small antimicrobial peptides capable of neutralizing human adenovirus (HAdV) by binding capsid proteins and blocking endosomal escape of virus. In humans, the alpha defensin HD5 is produced by...
4.
Aevermann B, Pickett B, Kumar S, Klem E, Agnihothram S, Askovich P, et al.
Sci Data
. 2015 May;
1:140033.
PMID: 25977790
The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This program...
5.
Selinger C, Tisoncik-Go J, Menachery V, Agnihothram S, Law G, Chang J, et al.
BMC Genomics
. 2014 Dec;
15:1161.
PMID: 25534508
Background: The recent emergence of a novel coronavirus in the Middle East (designated MERS-CoV) is a reminder of the zoonotic and pathogenic potential of emerging coronaviruses in humans. Clinical features...
6.
Rasmussen A, Okumura A, Ferris M, Green R, Feldmann F, Kelly S, et al.
Science
. 2014 Nov;
346(6212):987-91.
PMID: 25359852
Existing mouse models of lethal Ebola virus infection do not reproduce hallmark symptoms of Ebola hemorrhagic fever, neither delayed blood coagulation and disseminated intravascular coagulation nor death from shock, thus...
7.
Britton L, Sova P, Belisle S, Liu S, Chan E, Katze M, et al.
Proteomics
. 2014 Aug;
14(19):2226-30.
PMID: 25116026
HIV-1 replication requires the insertion of viral DNA into the host genome, which is catalyzed by HIV-1 integrase. This integration event can lead to vast changes in the chromatin landscape...
8.
Deep sequencing of HIV-infected cells: insights into nascent transcription and host-directed therapy
Peng X, Sova P, Green R, Thomas M, Korth M, Proll S, et al.
J Virol
. 2014 May;
88(16):8768-82.
PMID: 24850744
Unlabelled: Polyadenylated mature mRNAs are the focus of standard transcriptome analyses. However, the profiling of nascent transcripts, which often include nonpolyadenylated RNAs, can unveil novel insights into transcriptional regulation. Here,...
9.
Josset L, Menachery V, Gralinski L, Agnihothram S, Sova P, Carter V, et al.
mBio
. 2013 May;
4(3):e00165-13.
PMID: 23631916
Unlabelled: A novel human coronavirus (HCoV-EMC) was recently identified in the Middle East as the causative agent of a severe acute respiratory syndrome (SARS) resembling the illness caused by SARS...
10.
Chang S, Thomas M, Sova P, Green R, Palermo R, Katze M
mBio
. 2013 Feb;
4(1):e00549-12.
PMID: 23386435
HIV infection of CD4(+) T cells induces a range of host transcriptional changes in mRNAs as well as microRNAs that may coordinate changes in mRNAs. To survey these dynamic changes,...